| 7EU1 |
EM |
Eukaryote |
Arabidopsis thaliana |
The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme
|
34941388 |
3.86Å |
RNAP |
RNAP |
ZN,MG |
| 5FLM |
EM |
Eukaryote |
Bos taurus |
Structure of transcribing mammalian RNA polymerase II |
26789250 |
3.40 Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5OIK |
EM |
Eukaryote |
Bos taurus |
Structure of an RNA polymerase II-DSIF transcription elongation complex |
28892040 |
3.70Å |
EC |
RNA polymerase II,Spt4,Spt5 |
ZN MG |
| 7A8P |
EM |
Eukaryote |
Homo sapiens |
Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor. |
33328633 |
3.50Å |
Enzyme |
DNA-directed RNA polymerase, mitochondrial |
R4Q[ (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid ] |
| 2XUB |
XRD |
Eukaryote |
Homo sapiens |
Human RPC62 subunit structure |
21358628 |
2.80Å |
RNAP |
RPC3 |
|
| 2XV4 |
XRD |
Eukaryote |
Homo sapiens |
Structure of human RPC62 (partial) |
21358628 |
2.95Å |
RNAP |
RPC3 |
PO4 |
| 5AFQ |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of RPC62 - RPC32 beta |
26394183 |
7.00Å |
RNAP |
RPC3,RPC32 BETA (RPC7L) |
|
| 2GHQ |
XRD |
Eukaryote |
Homo sapiens |
CTD-specific phosphatase SCP1 in complex with peptide C-terminal domain of RNA polymerase II |
17157258 |
2.05 Å |
RNAP |
RNAP II largest subunit,Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
MG |
| 2GHT |
XRD |
Eukaryote |
Homo sapiens |
CTD-specific phosphatase SCP1 in complex with peptide from C-terminal domain of RNA polymerase II |
17157258 |
1.80 Å |
RNAP |
RNAP II largest subunit,Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
MG |
| 2LTO |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
TDRD3 complex |
23066109 |
|
Subunit |
TDRD3,RPB1 |
|
| 3D9L |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxyl-terminal domain of RNA-polymerase II |
18550522 |
2.20 Å |
CTD |
CTD-peptide,RNA-binding protein 16 |
GOL ACT |
| 3D9M |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxy-terminal domain of RNA-polymerase II |
18550522 |
2.20 Å |
CTD |
CTD-peptide,RNA-binding protein 16 |
SO4 NH4 |
| 3D9N |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxy-terminal domain of RNA-polymerase II |
18550522 |
2.20 Å |
CTD |
CTD-peptide,RNA-binding protein 16 |
SO4 |
| 3D9O |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxy-terminal domain of RNA-polymerase II |
18550522 |
2.20 Å |
CTD |
CTD-peptide,RNA-binding protein 16 |
SO4 NH4 |
| 3D9P |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxy-terminal domain of RNA-polymerase II |
18550522 |
2.20 Å |
CTD |
CTD-peptide,RNA-binding protein 16 |
SO4 |
| 4JXT |
XRD |
Eukaryote |
Homo sapiens |
CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD |
24997600 |
1.90 Å |
Subunit |
RPRD1A, RPRD1B |
UNX[ UNKNOWN ATOM OR ION ] |
| 5IY6 |
EM |
Eukaryote |
Homo sapiens |
Human holo-PIC in the closed state |
27193682 |
7.20 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IY7 |
EM |
Eukaryote |
Homo sapiens |
Human holo-PIC in the open state |
27193682 |
8.60 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IY8 |
EM |
Eukaryote |
Homo sapiens |
Human holo-PIC in the initial transcribing state |
27193682 |
7.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IY9 |
EM |
Eukaryote |
Homo sapiens |
Human holo-PIC in the initial transcribing state (no IIS) |
27193682 |
6.30 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IYA |
EM |
Eukaryote |
Homo sapiens |
Human core-PIC in the closed state |
27193682 |
5.40 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1 |
ZN MG |
| 5IYB |
EM |
Eukaryote |
Homo sapiens |
Human core-PIC in the open state |
27193682 |
3.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1 |
ZN MG |
| 5IYC |
EM |
Eukaryote |
Homo sapiens |
Human core-PIC in the initial transcribing state |
27193682 |
3.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1 |
ZN MG |
| 5IYD |
EM |
Eukaryote |
Homo sapiens |
Human core-PIC in the initial transcribing state (no IIS) |
27193682 |
3.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF |
ZN MG |
| 6DRD |
EM |
Eukaryote |
Homo sapiens |
RNA pol II(g) |
30190596 |
3.90Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,GRinL1A |
ZN |
| 6O9L |
EM |
Eukaryote |
Homo sapiens |
Human holo-PIC in the closed state |
31110295 |
7.20 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,TEFA protein 1,TFIIH,MAT1,CDK,Cyclin-H |
SF4[ IRON/SULFUR CLUSTER ] ZN MG |
| 2C35 |
XRD |
Eukaryote |
Homo sapiens |
Subunits RPB4 and RPB7 of human RNA polymerase II |
16282592 |
2.70 Å |
RNAP |
RNAP II 16/19 kDa polypeptide |
|
| 1QKL |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Hrpabc14.4, essential subunit of human RNA polymerases I, II and III |
10542096 |
|
RNAP |
RNAP II 14.4 kDa polypeptide |
|
| 2F3I |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution structure of a subunit of RNA polymerase II |
16632472 |
|
RNAP |
RNAP I, II, and III 17.1 kDa polypeptide |
|
| 4LT6 |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human poly(A) polymerase gamma |
24076191 |
2.79 Å |
RNAP |
Poly(A) polymerase gamma |
3AT[ 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE ] CA |
| 3NR5 |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human MAF1 |
20887893 |
1.55 Å |
TF |
MAF1 |
|
| 1J2X |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of RAP74 C-terminal domain complexed with FCP1 C-terminal peptide |
12591941 |
2.00 Å |
TF |
TFIIF-alpha subunit,FCP1 |
SO4 ZN |
| 2K7L |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
NMR structure of a complex formed by the C-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 |
19215094 |
|
TF |
TFIIF Subunit RAP74,FCP1 |
|
| 1ONV |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
NMR structure of a complex containing the TFIIF subunit RAP74 and the RNAP II CTD phosphatase FCP1 |
12732728 |
|
TF |
TFIIF Subunit RAP74,FCP1 |
|
| 4RGW |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of a TAF1-TAF7 complex in human TFIID |
25412659 |
2.30 Å |
TF |
TFIID subunit 1/7 |
GOL |
| 5FUR |
EM |
Eukaryote |
Homo sapiens |
Structure of human TFIID-IIA bound to core promoter DNA |
27007846 |
8.50 Å |
TF |
TBP,TFIIA Subunit 1/2,TFIID Sununit 1/2/6/7/8 |
|
| 6MZL |
EM |
Eukaryote |
Homo sapiens |
Human TFIID canonical state |
30442764 |
23.0 Å |
TF |
TFIID,TBP,poly(UNK) |
|
| 6MZM |
EM |
Eukaryote |
Homo sapiens |
Human TFIID bound to promoter DNA and TFIIA |
30442764 |
7.50 Å |
TF |
TFIID,TFIIA,TBP |
|
| 6F3T |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the human TAF5-TAF6-TAF9 complex |
30510221 |
2.50 Å |
TF |
TFIID TAF5/TAF6/TAF9 |
CL |
| 6MZD |
EM |
Eukaryote |
Homo sapiens |
Human TFIID lobe a canonical |
30442764 |
9.80 Å |
TF |
TFIID,TBP,poly(UNK) |
|
| 6MZC |
EM |
Eukaryote |
Homo sapiens |
Human TFIID BC core |
30442764 |
4.50 Å |
TF |
TFIID,poly(UNK) |
|
| 4M6T |
XRD |
Eukaryote |
Homo sapiens |
Structure of human PAF1 and LEO1 complex |
24038468 |
2.50 Å |
TF |
LEO1,PAF1 |
SAM[ S-ADENOSYLMETHIONINE ] |
| 5ZYQ |
XRD |
Eukaryote |
Homo sapiens |
The structure of human PAF1/CTR9 complex |
30228257 |
2.53 Å |
TF |
CTR9 homolog,PAF1 |
|
| 3SPA |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human mitochondrial RNA polymerase |
21947009 |
2.50 Å |
RNAP |
RNAP(mitochondrial),Nonamer peptide |
SO4,GOL, CL |
| 4BOC |
XRD |
Eukaryote |
Homo sapiens |
Structure of mitochondrial RNA polymerase elongation complex |
24096365 |
2.65 Å |
EC |
RNAP(mitochondrial) |
|
| 5OLA |
XRD |
Eukaryote |
Homo sapiens |
Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM |
29033127 |
3.90 Å |
EC |
TEF(mitochondrial),RNAP(mitochondrial) |
|
| 6ERP |
XRD |
Eukaryote |
Homo sapiens |
Structure of the human mitochondrial transcription initiation complex at the LSP promoter |
29149603 |
4.50 Å |
IC |
TFA(mitochondrial),RNAP(mitochondrial),Dimethyladenosine transferase 2(mitochondrial) |
|
| 6ERQ |
XRD |
Eukaryote |
Homo sapiens |
Structure of the human mitochondrial transcription initiation complex at the HSP promoter |
29149603 |
4.50 Å |
IC |
TFA(mitochondrial),RNAP(mitochondrial),Dimethyladenosine transferase 2(mitochondrial) |
|
| 5ODD |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Human MED26 N-terminal domain (1-92) |
26861138 |
|
Med |
Mediator of RNAP II subunit 26 |
|
| 6H02 |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human mediator subunit MED23 |
30140054 |
2.80 Å |
Med |
Mediator of RNAP II subunit 23,LAMA nanobody NB106 |
|
| 1H3O |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the human TAF4-TAF12 (TAFII135-TAFII20) complex |
12237304 |
2.30 Å |
TF |
TFIID 20/15 kDa subunit/135 kDa subunit |
|
| 2P6V |
XRD |
Eukaryote |
Homo sapiens |
Structure of tafh domain of the human TAF4 subunit of TFIID |
17483474 |
2.00 Å |
TF |
TFIID subunit 4 |
SO4 |
| 2KY6 |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Structure of ARC92VBD/MED25ACID |
21378963 |
|
Med |
MED25 |
|
| 2L23 |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
NMR structure of the acid (activator interacting domain) of the human mediator MED25 protein |
20974256 |
|
Med |
MED25 |
|
| 2L6U |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution NMR structure of MED25(391-543) comprising the activator-interacting domain (acid) of human mediator subuniti 25. Northeast structural genomics consortium target HR6188A |
21785987 |
|
Med |
MED25 |
|
| 2XNF |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
The mediator MED25 activator interaction domain: structure and cooperative binding of VP16 subdomains |
21378965 |
|
Med |
MED25 |
|
| 4L1U |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human RTF1 plus3 domain in complex with Spt5 CTR phosphopeptide |
24101474 |
2.42 Å |
TF |
RTF1 homolog,Spt5 |
SO4 GOL |
| 4L1P |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human RTF1 plus3 domain |
24101474 |
2.12 Å |
TF |
RTF1 homolog |
GOL |
| 3U1U |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of RNA polymerase-associated protein RTF1 homolog plus-3 domain |
To be published. |
1.80 Å |
TF |
RTF1 homolog |
SO4 GOL UNX |
| 2DB9 |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution structure of the plus-3 domain of human KIAA0252 protein |
To be published. |
|
Subunit |
PAF1/RNA polymerase II complex |
|
| 2BZE |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
NMR structure of human RTF1 plus3 domain. |
18184592 |
|
TF |
KIAA0252 protein |
|
| 3PQ1 |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human mitochondrial poly(A) polymerase (PAPD1) |
21292163 |
3.10 Å |
RNAP |
Poly(A) RNA polymerase |
|
| 1PCF |
XRD |
Eukaryote |
Homo sapiens |
Human transcription coactivator PC4 C-terminal domain |
9360603 |
1.74 Å |
TF |
PC4 |
|
| 2C62 |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the human transcription cofactor PC4 in complex with single-stranded DNA |
16415882 |
1.74 Å |
TF |
P15(PC4) |
SO4 |
| 4USG |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of PC4 W89Y mutant complex with DNA |
25739870 |
1.97 Å |
TF |
P15(PC4) |
|
| 2Q5E |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human carboxy-terminal domain RNA polymerase II polypeptide a small phosphatase 2 |
18058037 |
2.51 Å |
RNAP |
SCP2 |
MG |
| 3O2Q |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex |
20861839 |
2.40 Å |
TF |
Symplekin,Ssu72, CTD Serine-5 phosphopeptide |
PO4 |
| 3O2S |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the human symplekin-Ssu72 complex |
20861839 |
2.50 Å |
TF |
Symplekin,Ssu72 |
PO4 |
| 4H3H |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of a Ternary complex of human symplekin ntd, human Ssu72 and a RNA poymerase II CTD peptide phosphorylated at Ser-7 |
23070812 |
2.20 Å |
TF |
Symplekin,Ssu72,Pol II CTD peptide |
PO4 |
| 4H3K |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of a Ternary complex of human symplekin ntd, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7 |
23070812 |
2.00 Å |
TF |
Symplekin,Ssu72,,Hexapeptide |
PO4 |
| 2E5N |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution structure of the ELL_N2 domain of target of RNA polymerase II elongation factor ELL2 |
To be published. |
|
TF |
ELL2 |
|
| 5JW9 |
XRD |
Eukaryote |
Homo sapiens |
The crystal structure of ELL2 oclludin domain and AFF4 peptide |
28134250 |
2.00 Å |
EF |
ELL2,AF4/FMR2 family member 4 |
|
| 4C9B |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of eIF4AIII-CWC22 complex |
24218557 |
2.00 Å |
IF |
eIF4AIII,CWC22 HOMOLOG |
PO4 GOL |
| 6YVH |
XRD |
Eukaryote |
Homo sapiens |
CWC22-CWC27-EIF4A3 complex |
32329775 |
3.19 Å |
IF |
eIF4AIII,CWC22 homolog,CWC27 homolog |
|
| 2HXY |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of human apo-eIF4AIII |
16931718 |
3.30 Å |
IF |
apo-eIF4AIII |
|
| 2BZ2 |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution structure of NELF E RRM |
16898873 |
|
EF |
NELF E |
|
| 2JX2 |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution conformation of RNA-bound NELF-E RRM |
18303858 |
|
EF |
NELF E |
|
| 5OOB |
XRD |
Eukaryote |
Homo sapiens |
Complex of human nuclear cap-binding complex with m7-GTP and NELF-E C-terminal peptide |
29101316 |
2.79 Å |
EF |
NELF E,Nuclear cap-binding protein subunit 1/2 |
MGT[ 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE ] |
| 2MMY |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution structure of the RNA recognition motif of human TAF15 |
26612539 |
|
IF |
TAF15 |
|
| 3D9I |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxy-terminal domain of RNA-polymerase II |
18550522 |
1.91 Å |
TF |
SCAF8 |
SO4 GOL NH4 |
| 3D9J |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxy-terminal domain of RNA-polymerase II |
18550522 |
1.60 Å |
TF |
SCAF8 |
SO4 GOL NH4 |
| 3D9K |
XRD |
Eukaryote |
Homo sapiens |
Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxy-terminal domain of RNA-polymerase II |
18550522 |
2.20 Å |
TF |
CTD-PEPTIDE,SCAF8 |
SO4 |
| 6EQY |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
4th KOW domain of human hSpt5 |
30076330 |
|
TF |
Spt5 |
|
| 6ER0 |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
6th KOW domain of human hSpt5 |
30076330 |
|
TF |
Spt5 |
|
| 2DO3 |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution structure of the third KOW motif of transcription elongation factor Spt5 |
To be published. |
|
TF |
Spt5 |
|
| 2E6Z |
SOLUTIONNMR |
Eukaryote |
Homo sapiens |
Solution structure of the second KOW motif of human transcription elongation factor Spt5 |
To be published. |
|
TF |
Spt5 |
|
| 2E+070 |
SOLUTION NMR |
Eukaryote |
Homo sapiens |
Solution structure of the fifth KOW motif of human transcription elongation factor Spt5 |
To be published. |
|
TF |
Spt5 |
|
| 3H7H |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the human transcription elongation factor DSIF, hSpt4/hSpt5 (176-273) |
19860741 |
1.55 Å |
TF |
Spt4,Spt5 |
BME[ BETA-MERCAPTOETHANOL ], ZN |
| 5OHO |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the KOWX-KOW4 domain of human DSIF |
28892040 |
1.60 Å |
EF |
Spt5 |
GOL CL |
| 5OHQ |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of the KOW6-KOW7 domain of human DSIF |
28892040 |
1.10 Å |
EF |
Spt5 |
CL NA |
| 7A6H |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of human apo RNA Polymerase III |
33558764 |
3.30 Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
SF4[ IRON/SULFUR CLUSTER ],ZN ,MG |
| 7AE1 |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of human RNA Polymerase III elongation complex 1 |
33558764 |
2.80Å |
EC |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
SF4[ IRON/SULFUR CLUSTER ],ZN ,MG |
| 7AE3 |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of human RNA Polymerase III elongation complex 3 |
33558764 |
3.10Å |
EC |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
SF4[ IRON/SULFUR CLUSTER ],ZN ,MG |
| 7AEA |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of human RNA Polymerase III elongation complex 2 |
33558764 |
3.40Å |
EC |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
SF4[ IRON/SULFUR CLUSTER ],ZN ,MG |
| 7AST |
EM |
Eukaryote |
Homo sapiens |
Apo Human RNA Polymerase III |
33335104 |
4.00Å |
RNAP |
RPC1,RPC10,RPABC5,RPABC4,RPABC3,RPABC2,RPABC1,RPAC2,RPAC1,RPC9,RPC8,RPC5,RPC4,RPC2,RPC6,RPC3,RPC7-beta |
|
| 7ASU |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of tWHD1 of Rpc5 subunit of human RNA Polymerase III
|
33335104 |
2.23Å |
RNAP |
RPC5 |
ZN |
| 7ASV |
XRD |
Eukaryote |
Homo sapiens |
Crystal structure of tWHD2 of Rpc5 subunit of human RNA Polymerase III |
33335104 |
1.55Å |
RNAP |
RPC5 |
ACT |
| 7D58 |
EM |
Eukaryote |
Homo sapiens |
cryo-EM structure of human RNA polymerase III in elongating state |
33558766 |
2.90Å |
EC |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
SF4[ IRON/SULFUR CLUSTER ],ZN |
| 7D59 |
EM |
Eukaryote |
Homo sapiens |
cryo-EM structure of human RNA polymerase III in apo state |
33558766 |
3.10Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
SF4[ IRON/SULFUR CLUSTER ],ZN |
| 7DN3 |
EM |
Eukaryote |
Homo sapiens |
Structure of Human RNA Polymerase III elongation complex |
33674783 |
3.50Å |
EC |
RPC1,RPC2,RPAC1,RPC8,RPC10,RPAC2,RPABC4,RPC6,RPABC1,RPABC2,RPABC3,RPABC5,RPC3,RPC7RPC9,RPC5,RPC4 |
SF4[ IRON/SULFUR CLUSTER ],ZN ,MG |
| 7DU2 |
EM |
Eukaryote |
Homo sapiens |
RNA polymerase III EC complex in post-translocation state |
33674783 |
3.35Å |
EC |
RPC1,RPC2,RPAC1,RPC8,RPAC2,RPABC4,RPC6,RPABC1,RPABC2,RPABC3,RPABC5,RPC3,RPC7,RPC9,RPC5,RPC4,RPC10 |
SF4[ IRON/SULFUR CLUSTER ],ZN ,MG |
| 7D59 |
EM |
Eukaryote |
Homo sapiens |
cryo-EM structure of human RNA polymerase III in apo state
|
33558766 |
3.10Å |
RNAP |
RNAP |
SF4,ZN |
| 7D58 |
EM |
Eukaryote |
Homo sapiens |
cryo-EM structure of human RNA polymerase III in elongating state
|
33558766 |
2.90Å |
EC |
RNAP |
SF4,ZN |
| 7FJI |
EM |
Eukaryote |
Homo sapiens |
human Pol III elongation complex
|
34675218 |
3.60Å |
EC |
RNAP |
SF4,ZN |
| 7OB9 |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of human RNA Polymerase I in elongation state |
34887565 |
2.70Å |
RNAP |
RNAP |
ZN,MG |
| 7OBA |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of human RNA Polymerase I in complex with RRN3 |
34887565 |
3.10Å |
RNAP |
RNAP |
ZN |
| 7OBB |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of human RNA Polymerase I Open Complex |
34887565 |
3.30Å |
RNAP |
RNAP |
ZN |
| 7LBM |
EM |
Eukaryote |
Homo sapiens |
Structure of the human Mediator-bound transcription pre-initiation complex |
33707221 |
4.80Å |
RNAP |
Isoform 2 of Mediator of RNA polymerase II transcription subunit 16,Mediator of RNA polymerase II transcription subunit 23,subunit 24,subunit 25,RNAP,Transcription initiation factor IIA subunit 1,subunit 2,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIE subunit 1,subunit beta,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,TFIIH basal transcription factor complex helicase XPB subunit,TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 4, p52,General transcription factor IIH subunit 2,General transcription factor IIH subunit 3,General transcription factor IIH subunit 5,CDK-activating kinase assembly factor MAT1,Cyclin-dependent kinase 7,Cyclin-H,Mediator of RNA polymerase II transcription subunit 6,subunit 8,subunit 11,subunit 17,subunit 18,subunit 20,subunit 22,subunit 27,subunit 28,subunit 29,subunit 30,subunit 14,subunit 4,subunit 7,subunit 9,subunit 10,subunit 19,subunit 21,subunit 31,subunit 15 |
SF4,ZN |
| 7VBB |
EM |
Eukaryote |
Homo sapiens |
Structure of the post state human RNA Polymerase I Elongation Complex |
34671025 |
2.81 Å |
EC |
DNA-directed RNA polymerase I subunit RPA1,RPA2,RPA12,RPA34,RPA43,RPA49,RPAC1,RPAC2,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5, |
ZN,MG |
| 8A43 |
EM |
Eukaryote |
Homo sapiens |
Human RNA polymerase I |
36271492 |
4.09 Å |
RNAP |
DNA-directed RNA polymerase I subunit RPA1,RPA2,RPA12,RPA34,RPA49,RPAC1,RPAC2,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5 |
|
| 7PZP |
EM |
Eukaryote |
Homo sapiens |
Mitochondrial DNA dependent RNA polymerase homodimer. |
35662414 |
3.50 Å |
RNAP |
DNA-directed RNA polymerase, mitochondrial |
|
| 7DTI |
SOLUTION NMR |
Eukaryote |
Homo sapiens |
Solution structure of the complex between RNA polymerase subunit RPB6 and TFIIH p62 PH domain |
34268577 |
|
RNAP |
RPABC2,General transcription factor IIH subunit 1 |
|
| 7ZC4 |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of POLRMT mutant. |
35662414 |
3.24 Å |
RNAP |
DNA-directed RNA polymerase, mitochondrial |
|
| 7ZXE |
EM |
Eukaryote |
Homo sapiens |
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) |
36424526 |
3.50 Å |
PIC |
Transcription initiation factor IIB,Transcription initiation factor IIB,Transcription initiation factor IIA subunit 1,2,snRNA-activating protein complex subunit 1,3,4,5 |
ZN |
| 7FJJ |
EM |
Eukaryote |
Homo sapiens |
human Pol III pre-termination complex
|
34675218 |
3.60Å |
TC |
RNAP |
SF4,ZN |
| 7PZR |
EM |
Eukaryote |
Homo sapiens |
Cryo-EM structure of POLRMT in free form. |
|
3.00 Å |
RNAP |
DNA-directed RNA polymerase, mitochondrial |
|
| 7YCX |
EM |
Eukaryote |
Homo sapiens, Sus scrofa |
The structure of INTAC-PEC complex |
36869814 |
4.18 Å |
RNAP |
Integrator complex subunit 1,Integrator complex subunit 2,Integrator complex subunit 4,Integrator complex subunit 5,Integrator complex subunit 6,Integrator complex subunit 7,Integrator complex subunit 8,Integrator complex subunit 9,Integrator complex subunit 11,Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform,Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, CTD1, CTD2, CTD3, CTD4,DNA-directed RNA polymerase subunit beta,RPB3,RPB4,RPB7,RPB9,RPB12,DNA-directed RNA polymerase II subunit E,DNA-directed RNA polymerase II subunit F,RPABC3,RPABC5,RNA_pol_L_2 domain-containing protein,Negative elongation factor A,Negative elongation factor B,Negative elongation factor C/D,Negative elongation factor E,Transcription elongation factor SPT4,Transcription elongation factor SPT5, |
ZN,MN,MG |
| 8BVW |
EM |
Eukaryote |
Homo sapiens, Sus scrofa, unidentified adenovirus, Xenopus laevis |
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) |
37148879 |
4.00 Å |
PIC |
General transcription and DNA repair factor IIH helicase subunit XPB,TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,General transcription factor IIH subunit 4,General transcription factor IIH subunit 2,General transcription factor IIH subunit 3,General transcription factor IIH subunit 5,CDK-activating kinase assembly factor MAT1,Cyclin-dependent kinase 7,Cyclin-H,DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RPB11-a,RNA polymerase II subunit D,DNA-directed RNA polymerase II subunit E,F,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,General transcription factor IIE subunit 1,Transcription initiation factor IIE subunit beta,Unassigned peptide, likely XPB,Unassigned peptide, likely TFIIE-beta,Histone H3.2,Histone H4,Histone H2A type 1,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 8BYQ |
EM |
Eukaryote |
Homo sapiens, Sus scrofa, unidentified adenovirus, Xenopus laevis |
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) |
37148879 |
4.10 Å |
PIC |
General transcription and DNA repair factor IIH helicase subunit XPB,TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,General transcription factor IIH subunit 4,General transcription factor IIH subunit 2,General transcription factor IIH subunit 3,General transcription factor IIH subunit 5,CDK-activating kinase assembly factor MAT1,Cyclin-dependent kinase 7,Cyclin-H,DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RPB11-a,RNA polymerase II subunit D,DNA-directed RNA polymerase II subunit E,F,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,General transcription factor IIE subunit 1,Transcription initiation factor IIE subunit beta,Unassigned peptide, likely XPB,Unassigned peptide, likely TFIIE-beta,Histone H3.2,Histone H4,Histone H2A type 1,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 8GXQ |
EM |
Eukaryote |
Homo sapiens, Xenopus laevis, Sus scrofa |
PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state |
36201575 |
5.04 Å |
PIC |
Transcription initiation factor IIB,Transcription initiation factor TFIID subunit 1,General transcription factor IIE subunit 1,General transcription factor IIF subunit 1,General transcription and DNA repair factor IIH helicase subunit XPD,Histone H3,DNA-directed RNA polymerase subunit,Transcription initiation factor TFIID subunit 2,Transcription initiation factor IIE subunit beta,General transcription factor IIF subunit 2,General transcription factor IIH subunit 1,Histone H4,DNA-directed RNA polymerase subunit beta,General transcription factor IIH subunit 4,RPB3,RPB4,RPB7,RPB9,RPB12,DNA-directed RNA polymerase II subunit E,F,RPABC3,RPABC5,RNA_pol_L_2 domain-containing protein,TATA-box-binding protein,Transcription initiation factor IIA subunit 1,2,3,4,5,6,9,10,11,12,13,7,8,CDK-activating kinase assembly factor MAT1,General transcription factor IIH subunit 3,General transcription factor IIH subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,General transcription factor IIH subunit 5,Cyclin-dependent kinase 7,Cyclin-H,Mediator of RNA polymerase II transcription subunit 1,4,6,7,8,9,10,11,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,HISTONE H2A.Z,Histone H2B |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 8GXS |
EM |
Eukaryote |
Homo sapiens, Xenopus laevis, Sus scrofa |
PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state |
36201575 |
4.16 Å |
PIC |
Transcription initiation factor IIB,Transcription initiation factor TFIID subunit 1,General transcription factor IIE subunit 1,General transcription factor IIF subunit 1,General transcription and DNA repair factor IIH helicase subunit XPD,Histone H3,DNA-directed RNA polymerase subunit,Transcription initiation factor TFIID subunit 2,Transcription initiation factor IIE subunit beta,General transcription factor IIF subunit 2,General transcription factor IIH subunit 1,Histone H4,DNA-directed RNA polymerase subunit beta,General transcription factor IIH subunit 4,RPB3,RPB4,RPB7,RPB9,RPB12,DNA-directed RNA polymerase II subunit E,F,RPABC3,RPABC5,RNA_pol_L_2 domain-containing protein,TATA-box-binding protein,Transcription initiation factor IIA subunit 1,2,3,4,5,6,9,10,11,12,13,7,8,CDK-activating kinase assembly factor MAT1,General transcription factor IIH subunit 3,General transcription factor IIH subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,General transcription factor IIH subunit 5,Cyclin-dependent kinase 7,Cyclin-H,Mediator of RNA polymerase II transcription subunit 1,4,6,7,8,9,10,11,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,HISTONE H2A.Z,Histone H2B |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 8H0V |
EM |
Eukaryote |
Homo sapiens,Komagataella phaffii |
RNA polymerase II transcribing a chromatosome (type I) |
36435862 |
3.80 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RNA polymerase II subunit,RPABC3,RPABC10-beta,RNA polymerase II subunit B12.5,RNA polymerase subunit ABC10-alpha,Histone H3.1,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,Histone H1.2 |
ZN,MG |
| 6A5R |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome |
30287617 |
8.70 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5L |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA |
30287617 |
5.60 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5O |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome |
30287617 |
9.90 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5P |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome |
30287617 |
7.00 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5T |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome |
30287617 |
6.70 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5U |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation |
30287617 |
7.60 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6inQ |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position) |
30287617 |
6.90 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6IR9 |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-1) of the nucleosome |
30733384 |
3.80 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4W |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-5) of the nucleosome |
30733384 |
7.90 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4X |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1a) |
30733384 |
4.30 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4Y |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1b) |
30733384 |
4.30 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4Z |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome |
30733384 |
4.10 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J51 |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome, weak ELF1 (+1 position) |
30733384 |
4.20 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5/4p |
ZN MG |
| 6J50 |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome (tilted conformation) |
30733384 |
4.70 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5/4p |
ZN MG |
| 7XN7 |
EM |
Eukaryote |
Komagataella phaffii |
RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C |
35981082 |
3.10 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RNA polymerase II subunit,RPABC3,RNA polymerase subunit ABC10-beta,RNA polymerase II subunit B12.5,RNA polymerase subunit ABC10-alpha,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Chromatin elongation factor SPT5,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
ZN,MG |
| 8H0W |
EM |
Eukaryote |
Komagataella phaffii, Homo sapiens |
RNA polymerase II transcribing a chromatosome (type II) |
36435862 |
4.60 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RNA polymerase II subunit,RPABC3,RPABC10-beta,RNA polymerase II subunit B12.5,RNA polymerase subunit ABC10-alpha,Histone H3.1,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,Histone H1.2 |
ZN,MG |
| 7XTD |
EM |
Eukaryote |
Komagataella phaffii, Homo sapiens |
RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) |
35981082 |
3.90 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RPABC3,RPABC10-alpha,RPABC10-beta,RNA polymerase II subunit,RNA polymerase II subunit B12.5,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p,Histone H3.3,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,FACT complex subunit,FACT complex subunit POB3 |
ZN,MG |
| 7XSX |
EM |
Eukaryote |
Komagataella phaffii, Homo sapiens |
RNA polymerase II elongation complex transcribing a nucleosome (EC49) |
35981082 |
3.80 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RPABC3,RPABC10-alpha,RPABC10-beta,RNA polymerase II subunit,RNA polymerase II subunit B12.5,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p,Histone H3.3,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,FACT complex subunit,FACT complex subunit POB3 |
ZN,MG |
| 7XTI |
EM |
Eukaryote |
Komagataella phaffii, Homo sapiens |
RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) |
35981082 |
3.90 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RPABC3,RPABC10-alpha,RPABC10-beta,RNA polymerase II subunit,RNA polymerase II subunit B12.5,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p,Histone H3.3,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,FACT complex subunit,FACT complex subunit POB3 |
ZN,MG |
| 7XT7 |
EM |
Eukaryote |
Komagataella phaffii, Homo sapiens |
RNA polymerase II elongation complex transcribing a nucleosome (EC49B) |
35981082 |
4.20 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RPABC3,RPABC10-alpha,RPABC10-beta,RNA polymerase II subunit,RNA polymerase II subunit B12.5,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p,Histone H3.3,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,FACT complex subunit,FACT complex subunit POB3 |
ZN,MG |
| 7XSE |
EM |
Eukaryote |
Komagataella phaffii,Homo sapiens |
RNA polymerase II elongation complex transcribing a nucleosome (EC42) |
35981082 |
3.60 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44, part of central core,RNA polymerase II subunit B32,RPABC1,RPABC3,RPABC23,RPABC10-alpha,RPABC10-beta,RNA polymerase II subunit,RNA polymerase II subunit B12.5,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Histone H3.3,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
ZN,MG |
| 7XSZ |
EM |
Eukaryote |
Komagataella phaffii,Homo sapiens |
RNA polymerase II elongation complex transcribing a nucleosome (EC115) |
35981082 |
3.40 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44, RNA polymerase II subunit B32,RPABC1,RPABC23,RNA polymerase II subunit,RPABC3,DNA-directed RNA polymerase subunit,RPABC10-alpha,RPABC10-beta,RNA polymerase II subunit B12.5,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p,Histone H3.3,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J |
ZN,MG |
| 7XSE |
EM |
Eukaryote |
Komagataella phaffii,Homo sapiens |
RNA polymerase II elongation complex transcribing a nucleosome (EC42) |
35981082 |
3.60 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44, part of central core,RNA polymerase II subunit B32,RPABC1,RPABC3,RPABC23,RPABC10-alpha,RPABC10-beta,RNA polymerase II subunit,RNA polymerase II subunit B12.5,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Histone H3.3,Histone H4,Histone H2A type 1-B/E,Histone H2B type 1-J,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
ZN,MG |
| 2J7N |
XRD |
Eukaryote |
Neurospora crassa |
Structure of the RNAi polymerase from neurospora crassa |
17147473 |
2.30 Å |
RNAP |
RNA-DEPENDENT RNA POLYMERASE |
GOL,MG |
| 2J7O |
XRD |
Eukaryote |
Neurospora crassa |
Structure of the RNAi polymerase from neurospora crassa |
17147473 |
3.50 Å |
RNAP |
RNA DEPENDENT RNA POLYMERASE |
MG |
| 7Y7S |
XRD |
Eukaryote |
Neurospora crassa |
QDE-1 in complex with DNA template, RNA primer and AMPNPP |
36039765 |
2.70 Å |
RNAP |
RNA-dependent RNA polymerase |
ZAN[5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine],PEG[DI(HYDROXYETHYL)ETHER],CA[CALCIUM ION],MG |
| 7Y7P |
XRD |
Eukaryote |
Neurospora crassa |
QDE-1 in complex with RNA template, RNA primer and AMPNPP |
36039765 |
2.70 Å |
RNAP |
RNA-dependent RNA polymerase |
ZAN[5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine],PEG[DI(HYDROXYETHYL)ETHER],GOL[GLYCEROL],CA[CALCIUM ION] |
| 7Y7Q |
XRD |
Eukaryote |
Neurospora crassa |
QDE-1 in complex with RNA template, RNA primer and 3'-dGTP |
36039765 |
2.05 Å |
RNAP |
RNA-dependent RNA polymerase |
GTP[GUANOSINE-5'-TRIPHOSPHATE],PEG[ DI(HYDROXYETHYL)ETHER],GOL[GLYCEROL],CA[CALCIUM ION],MG |
| 7Y7R |
XRD |
Eukaryote |
Neurospora crassa |
QDE-1 in complex with DNA template, RNA primer and 3'-dGTP |
36039765 |
2.10 Å |
RNAP |
RNA-dependent RNA polymerase |
GTP[GUANOSINE-5'-TRIPHOSPHATE],PEG[ DI(HYDROXYETHYL)ETHER],GOL[GLYCEROL],CA[CALCIUM ION],MG |
| 7Y7T |
XRD |
Eukaryote |
Neurospora crassa |
QDE-1 in complex with 12nt DNA template, ATP and 3'-dGTP |
36039765 |
2.50 Å |
RNAP |
RNA-dependent RNA polymerase |
GTP[GUANOSINE-5'-TRIPHOSPHATE],ATP[ADENOSINE-5'-TRIPHOSPHATE],MG |
| 2RF4 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of the RNA polymerase I subcomplex A14/43 |
18160037 |
3.10 Å |
RNAP |
RPA4 |
|
| 4C2M |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of RNA polymerase I at 2.8 angstrom resolution |
24153182 |
2.80 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN SO4 |
| 4C3H |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of 14-subunit RNA polymerase I at 3.27 angstrom resolution, crystal form c2-93 |
24153184 |
3.27 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 4C3I |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of 14-subunit RNA polymerase I at 3.0 angstrom resolution, crystal form c2-100 |
24153184 |
3.00 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
MPD[ (4S)-2-METHYL-2,4-PENTANEDIOL ], SO4, ZN ,MG |
| 4C3J |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of 14-subunit RNA polymerase I at 3.35 angstrom resolution, crystal form c2-90 |
24153184 |
3.35 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 4YM7 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I structure with an alternative dimer hinge |
26327374 |
5.50 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 5G5L |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I-Rrn3 complex at 4.8 a resolution |
27418309 |
4.80 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3 |
ZN |
| 5LMX |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Monomeric RNA polymerase I at 4.9 angstrom resolution |
28262097 |
4.90 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 5M3F |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase I elongation complex at 3.8 angstrom |
27842382 |
3.80 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
SO4 ZN MG |
| 5M3M |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Free monomeric RNA polymerase I at 4.0 angstrom resolution |
27842382 |
4.00 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
SO4 ZN |
| 5M5W |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I open complex |
27867008 |
3.80 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 5M5X |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I elongation complex 1 |
27867008 |
4.00 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 5M5Y |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I elongation complex 2 |
27867008 |
4.00 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 5M64 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I elongation complex with A49 tandem winged helix domain |
27867008 |
4.60 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 5N5Y |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
cryo-EM structure of RNA polymerase I in complex with Rrn3 and core factor (orientation III) |
28340337 |
7.70 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
SO4 ZN MG |
| 5N5Z |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
cryo-EM structure of RNA polymerase I in complex with Rrn3 and core factor (orientation II) |
28340337 |
7.70 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN |
| 5N60 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
cryo-EM structure of RNA polymerase I in complex with Rrn3 and core factor (orientation I) |
28340337 |
7.70 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN |
| 5N61 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I initially transcribing complex |
28340337 |
3.40 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
SO4 ZN MG |
| 5OA1 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I pre-initiation complex |
28739580 |
4.40 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN |
| 5W5Y |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I initial transcribing complex |
28623663 |
3.80 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF RRN6/RRN7/RRN11 |
ZN |
| 5W64 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I initial transcribing complex state 1 |
28623663 |
4.20 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF RRN6/RRN7/RRN11 |
ZN |
| 5W65 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I initial transcribing complex state 2 |
28623663 |
4.30 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF RRN6/RRN7/RRN11 |
ZN |
| 5W66 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I initial transcribing complex state 3 |
28623663 |
3.90 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF RRN6/RRN7/RRN11 |
ZN |
| 6H67 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) |
30127008 |
3.60 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN MG |
| 6H68 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) with fully-ordered A49 |
30127008 |
4.60 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 6HKO |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP |
30913026 |
3.42 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,GMPCPP |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ],ZN, MG |
| 6HLQ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP |
30913026 |
3.18 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ],ZN, MG |
| 6HLR |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) |
30913026 |
3.18 Å |
EC |
RPA190/RPA135/RPA14/RPA43/RPA12,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ],ZN, MG |
| 6HLS |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast apo RNA polymerase I* |
30913026 |
3.21 Å |
RNAP |
RPA190/RPA135/RPA14/RPA43/RPA12,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5 |
ZN |
| 6RQH |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I closed conformation 1 (CC1) |
31804486 |
3.70 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
|
| 6RQL |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I closed conformation 2 (CC2) |
31804486 |
2.90 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
|
| 6RQT |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I-tWH-Rrn3-DNA |
To be published. |
4.00 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3 |
ZN |
| 6RRD |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I pre-initiation complex DNA opening intermediate 1 |
31804486 |
3.10 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN |
| 6RUI |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I pre-initiation complex DNA opening intermediate 2 |
31804486 |
2.70 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN |
| 6RUO |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I open complex conformation 1 |
31804486 |
3.50 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN |
| 6RWE |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase I open complex conformation 2 |
31804486 |
3.00 Å |
IC |
RPA190/RPA135/RPA14/RPA43/RPA12/RPA49/RPA34,RPAC1/RPAC2,RPABC1/RPABC2/RPABC3/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN |
| 5O7X |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Rystal structure of S. Cerevisiae core factor at 3.2 angstrom resolution |
28340337 |
3.20 Å |
|
TIF RRN6,RRN7,RRN11 |
SO4 MG |
| 3NFI |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 |
20797630 |
1.90 Å |
Subunit |
RPA49 |
PE4[ 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL ] |
| 3NFH |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (p4) |
20797630 |
2.17 Å |
Subunit |
RPA49 |
|
| 6TPS |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Early intermediate RNA polymerase I pre-initiation complex - eipic |
32139698 |
3.54 Å |
IC |
RPA12/RPA14/RPA34/RPA43/RPA49/RPA135/RPA190,RPAC1/RPAC2,RPABC1/RPABC2/RPABC4/RPABC5,TIF Rrn3/RRN6/RRN7/RRN11 |
ZN MG |
| 5FJ9 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
cryo-EM structure of yeast apo RNA polymerase III at 4.6 angstrom |
26605533 |
4.60 Å |
RNAP |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5 |
ZN |
| 5FJ8 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 angstrom |
26605533 |
3.90 Å |
EC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5 |
ZN |
| 5FJA |
EM |
Eukaryote |
Saccharomyces cerevisiae |
cryo-EM structure of yeast RNA polymerase III at 4.7 angstrom |
26605533 |
4.65 Å |
RNAP |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5 |
ZN |
| 6CNB |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase III initial transcribing complex |
30083386 |
4.10 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN |
| 6CNC |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase III open complex |
30083386 |
4.10 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN |
| 6CND |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase III natural open complex (nOC) |
30083386 |
4.80 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN |
| 6CNF |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase III elongation complex |
30083386 |
4.50 Å |
EC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN |
| 6EU0 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase III open pre-initiation complex (OC-PIC) |
29345637 |
4.00 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN MG |
| 6EU1 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase III - open DNA complex (OC-POL3) |
29345637 |
3.40 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5 |
ZN MG |
| 6EU2 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Apo RNA polymerase III - open conformation (oPOL3) |
29345637 |
3.40 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5 |
ZN MG |
| 6EU3 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Apo RNA polymerase III - closed conformation (cPOL3) |
29345637 |
3.30 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5 |
ZN MG |
| 6F40 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase III open complex |
29345638 |
3.70 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN |
| 6F41 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase III initially transcribing complex |
29345638 |
4.30 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN |
| 6F42 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase III closed complex CC1. |
29345638 |
5.50 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
ZN |
| 6F44 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase III closed complex CC2. |
29345638 |
4.20 Å |
IC |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,TFIIIB,TBP |
|
| 6TUT |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Cryo-EM structure of the RNA polymerase III-MAF1 complex |
32066962 |
3.25 Å |
RNAP |
RPC1/RPC2/RPC3/RPC4/RPC5/RPC6/RPC7/RPC8/RPC9/RPC10,RPAC1/RPAC2,RPABC 1/RPABC 2/RPABC 3/RPABC 4/RPABC 5,MAF1 |
ZN |
| 1NT9 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete 12-subunit RNA polymerase II |
12746495 |
4.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 1PQV |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II-TFIIS complex |
12914699 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIS |
ZN MG |
| 1WCM |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete 12-subunit RNA polymerase II at 3.8 angstrom |
15591044 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 1Y14 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of yeast subcomplex of RPB4 and RPB7 |
15591044 |
2.30 Å |
RNAP |
RPB4,RPB7 |
|
| 1Y1V |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Refined RNA polymerase II-TFIIS complex |
15610738 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIS |
ZN MG |
| 1Y1W |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex |
15610738 |
4.00Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 1Y1Y |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II-TFIIS-DNA/RNA complex |
15610738 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 1Y77 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex with substrate analogue GMPCPP |
15610738 |
4.50Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 2B63 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II-RNA inhibitor complex |
16341226 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2B8K |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
12-subunit RNA polymerase II |
16765890 |
4.15Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 2JA5 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex A |
17290000 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2JA6 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex B |
17290000 |
4.00Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2JA7 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex C |
17290000 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2JA8 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex D |
17290000 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2R7Z |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Cisplatin lesion containing RNA polymerase II elongation complex |
17994106 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
CPT[ Cisplatin ] ZN MG |
| 2R92 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Elongation complex of RNA polymerase II with artificial RDRP scaffold |
18004386 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2R93 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop |
18004386 |
4.00Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2VUM |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Alpha-amanitin inhibited complete RNA polymerase II elongation complex |
18552824 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3FKI |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
12-subunit RNA polymerase II refined with Zn-SAD data |
19289466 |
3.88Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3H3V |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNAP II containing poly(A)-signal sequence in the active site |
19535338 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOU |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex I with a T-U mismatch |
19560423 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3HOV |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex II |
19560423 |
3.50Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOW |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3-uridine |
19560423 |
3.60Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOX |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex VI |
19560423 |
3.65Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOY |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex VI |
19560423 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOZ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3-guanine |
19560423 |
3.65Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3I4M |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
8-oxoguanine containing RNA polymerase II elongation complex D |
19758983 |
3.70Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3I4N |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
8-oxoguanine containing RNA polymerase II elongation complex E |
19758983 |
3.90Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3J0K |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Orientation of RNA polymerase II within the human VP16-mediator-pol II-TFIIF assembly |
21468301 |
36.0Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3J1N |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Cryo-EM map of a yeast minimal preinitiation complex interacting with the mediator head module |
22579255 |
16.0Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 3K1F |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of RNA polymerase II in complex with TFIIB |
19820686 |
4.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
ZN |
| 3PO2 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Arrested RNA polymerase II elongation complex |
21346759 |
3.30Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
EPE[ 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID?? PEG??DI(HYDROXYETHYL)ETHER] ZN MG ACT[ ACETATE ION ] |
| 3PO3 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Arrested RNA polymerase II reactivation intermediate |
21346759 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
EPE[ 4-(2-HYDROXYETHYL)-2-PIPERAZINE ETHANESULFONIC ACID?? PEG??DI(HYDROXYETHYL)ETHER ] ZN MG ACT[ ACETATE ION ] |
| 3QT1 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II variant containing a chimeric RPB9-C11 subunit |
21454497 |
4.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3B |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3C |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3D |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid |
22056778 |
3.40Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3E |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.40Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ IPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A3F |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ IPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A3G |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3I |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II binary complex with DNA |
22056778 |
3.80Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3J |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP |
22056778 |
3.70Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 4A3K |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3L |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A3M |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.90Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A93 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex containing a CPD lesion |
22405652 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4BBR |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of RNA polymerase II-TFIIB complex |
23151482 |
3.40Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
ZN MG |
| 4BBS |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of an initially transcribing RNA polymerase II-TFIIB complex |
23151482 |
3.60Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
ZN MG |
| 4BXX |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Arrested RNA polymerase II-Bye1 complex |
24003114 |
3.28Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
ZN MG |
| 4BXZ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II-Bye1 complex |
24003114 |
4.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
ZN MG |
| 4BY1 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Elongating RNA polymerase II-Bye1 TLD complex soaked with AMPCPP |
24003114 |
3.60Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4BY7 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Elongating RNA polymerase II-Bye1 TLD complex |
24003114 |
3.15Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
EPE[ 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID ] ZN MG |
| 4V1N |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Architecture of the RNA polymerase II-mediator core transcription initiation complex |
25652824 |
7.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TBP,TFIIF subunit alpha,TFIIF subunit beta |
ZN MG |
| 4V1O |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Architecture of the RNA polymerase II-mediator core transcription initiation complex |
25652824 |
9.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TBP,TFIIF subunit alpha,TFIIF subunit beta,Mediator of RNA polymerase II transcription subunit 6/8/11/18/20/22 |
ZN MG |
| 5C3E |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
3.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5C44 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
3.95Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 5C4A |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
4.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5C4X |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5FMF |
EM |
Eukaryote |
Saccharomyces cerevisiae |
The P-lobe of RNA polymerase II pre-initiation complex |
26483468 |
6.00Å |
pIC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,DNA repair helicase RAD25 and SSL2,Transcription elongation factor S-II and DST1,RNA polymerase II pre-Initiation complex(TOA1),TFIIA subunit 2(TOA2), TFIIB(SUA7),TBP,TFIIE subunit alpha(TFA1),TFIIE subunit beta(TFA2),RNA polymerase II pre-Initiation complex (Tfg1),TFIIF subunit beta(TFG2),TFIIB subint 2(TFB2)/5(TFB5),DNA repair helicase RAD3 |
ZN MG |
| 5FYW |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Transcription initiation complex structures elucidate DNA opening (OC) |
27193681 |
4.35Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TBP,TFIIF subunit alpha,TFIIF subunit bata,TFIIA large subunit,TFIIA subunit 2,TFIIE subunit alpha,TFIIE subunit beta |
ZN MG |
| 5FZ5 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Transcription initiation complex structures elucidate DNA opening (CC) |
27193681 |
8.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit bata,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta |
ZN MG |
| 5IP7 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of RNA polymerase II-Tfg1 peptide complex |
27193681 |
3.52Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5IP9 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of RNA polymerase II-TFIIF complex |
27193681 |
3.90Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5OQJ |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of yeast transcription pre-initiation complex with TFIIH |
29088706 |
4.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,DNA repair helicase RAD3,RNA polymerase II transcription factor B subunit 1,RNA polymerase II transcription factor B subunit 2,RNA polymerase II transcription factor B subunit 3,RNA polymerase II transcription factor B subunit 4,RNA polymerase II transcription factor B subunit 5,Suppressor of stem-loop protein 1,DNA repair helicase RAD25 |
SF4[ IRON/SULFUR CLUSTER ] ZN MG |
| 5OQM |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of yeast transcription pre-initiation complex with TFIIH and core mediator |
29088706 |
5.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,subunit TFB2,subunit 3,subunit TFB4,subunit TFB5,subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Mediator of RNA polymerase II transcription subunit 6,subunit 8,subunit 11,subunit 17, subunit 18,subunit 20,subunit 22,subunit 4, subunit 7, subunit 9, subunit 10, subunit 14, subunit 19,subunit 21,subunit 31 |
SF4[ IRON/SULFUR CLUSTER ]ZN MG |
| 5OT2 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in the presence of 3D-Napht-A |
29087308 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
AHW[ 2-ethyl-7-methoxy-naphthalene ]ZN MG |
| 5SVA |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Mediator-RNA polymerase II pre-initiation complex |
27610567 |
15.3Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Mediator of RNA polymerase II transcription subunit 6,subunit 8,subunit 11,ubunit 17,subunit 18,subunit 20,subunit 22,subunit 4,subunit 7,subunit 9,subunit 21,subunit 31,DNA repair helicase RAD3,DNA repair helicase RAD25,RNA polymerase II transcription factor B subunit 2,RNA polymerase II transcription factor B subunit 5,Transcription initiation factor IIB,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,TBP,RPB1,Transcription initiation factor TFIID subunit 14 |
ZN MG |
| 5U5Q |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
12 subunit RNA polymerase II at room temperature collected using SFX |
28300169 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5VVR |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Ternary complex of RNA pol II, transcription scaffold and Rad26 |
29168508 |
5.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,DNA repair and recombination protein Rad26 |
ZN MG |
| 5VVS |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA pol II elongation complex |
29168508 |
6.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6GYK |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of a yeast closed complex (core CC1) |
30472190 |
5.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2 |
ZN MG |
| 6GYL |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of a yeast closed complex with distorted DNA (core CCdist) |
30472190 |
4.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Tfa1,Transcription initiation factor IIE subunit beta |
ZN MG |
| 6GYM |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of a yeast closed complex with distorted DNA (CCdist) |
30472190 |
6.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,General transcription and DNA repair factor IIH helicase subunit XPD,DNA repair helicase RAD3,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,RNA polymerase II transcription factor B subunit 4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,DNA repair helicase RAD25,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha |
SF4[ IRON/SULFUR CLUSTER ] ZN MG |
| 6I84 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of transcribing RNA polymerase II-nucleosome complex |
30575770 |
4.40Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.2,Histone H2A type 1,Histone H4,Histone H2B 1.1 |
ZN MG |
| 1I3Q |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II crystal form I at 3.1 angstrom resolution |
11313498 |
3.10 Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MG |
| 1I50 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II crystal form II |
11313498 |
2.80 Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MN |
| 1I6H |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II enlongation complex |
11313499 |
3.30Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MG |
| 1K83 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of yeast RNA polymerase II complexed with the inhibitor alpha amanitin |
11805306 |
2.80 Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MG |
| 1NIK |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Wild type RNA polymerase II |
12746498 |
4.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 1R5U |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II TFIIB complex |
14963322 |
4.50Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide,TFIIB |
ZN MG |
| 1R9S |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II strand separated elongation complex, matched nucleotide |
15537538 |
4.25Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
UTP ZN MG |
| 1R9T |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II strand separated elongation complex, mismatched nucleotide |
15537538 |
3.50Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ATP ZN MG |
| 1SFO |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II strand separated elongation complex |
14963331 |
3.61Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ZN MG |
| 1TWA |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II complexed with ATP |
15537538 |
3.20Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ATP ZN MN |
| 1TWC |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II complexed with GTP |
15537538 |
3.00Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
GTP ZN MN |
| 1TWF |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II complexed with UTP at 2.3 angstrom resolution |
15537538 |
2.30Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
UTP ZN MN |
| 1TWG |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II complexed with CTP |
15537538 |
3.30Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
CTP ZN MN |
| 1TWH |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II complexed with dATP |
15537538 |
3.40Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ATP ZN MN |
| 2E2H |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex at 5 mm MG2+ with GTP |
17129781 |
3.95Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
GTP ZN MG |
| 2E2I |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 5 mm mg+2 with dGTP |
17129781 |
3.41Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
DGT[ 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE ] ZN MG |
| 2E2J |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 5 mm mg+2 with GMPCPP |
17129781 |
3.50Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 2L0I |
SOLUTIONNMR |
Eukaryote |
Saccharomyces cerevisiae |
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide |
20818393 |
|
RNAP |
Regulator of Ty1 transposition protein 103,DNA-directed RNA polymerase CTD |
|
| 2LO6 |
SOLUTIONNMR |
Eukaryote |
Saccharomyces cerevisiae |
Structure of Nrd1 CID bound to phosphorylated RNAP II CTD |
22892239 |
|
CTD |
Protein NRD1,RPB1 |
|
| 2NVQ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 150 mm mg+2 with dUTP |
17129781 |
2.90Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
DUT[ DEOXYURIDINE-5'-TRIPHOSPHATE ] ZN MG |
| 2NVT |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 150 mm mg+2 with GMPCPP |
17129781 |
3.36Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 2NVX |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 5 mm mg+2 with dUTP |
17129781 |
3.60Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
DUT[ DEOXYURIDINE-5'-TRIPHOSPHATE ] ZN MG |
| 2NVY |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II form II in 150 mm MN+2 |
17129781 |
3.40Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
ZN MN |
| 2NVZ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with UTP, updated 11/2006 |
17129781 |
4.30Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
UTP ZN MG |
| 2YU9 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 150 mm mg+2 with UTP |
17129781 |
3.40Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140 kDa polypeptide,RNA polymerase II 45 kDa polypeptide,RNA polymerases I, II, and III 27 kDa polypeptide,RNA polymerases I, II, and III 23 kDa polypeptide,RNA polymerases I, II, and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
UTP ZN MG |
| 3CQZ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin |
18538653 |
2.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,ALPHA-AMANITin |
ZN |
| 3GTG |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 12mer RNA |
19478184 |
3.78Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTJ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 13mer RNA |
19478184 |
3.42Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTK |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 18mer RNA |
19478184 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3GTL |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 13mer with g<>u mismatch |
19478184 |
3.38Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTM |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Co-complex of backtracked RNA polymerase II with TFIIS |
19478184 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription elongation factor S-II |
ZN MG |
| 3GTP |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 24mer RNA |
19478184 |
3.90Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTQ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex induced by damage |
19478184 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3K7A |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of an RNA polymerase II-TFIIB complex |
19965383 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB |
ZN |
| 3M3Y |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex C |
20448203 |
3.18Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
C7P[ cis-diammine(pyridine)chloroplatinum(II) ] ZN MG |
| 3RZD |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3RZO |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 4-nt RNA |
21798951 |
3.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3S14 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 6-nt RNA |
21798951 |
2.85Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S15 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 7-nt RNA |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S16 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with an 8-nt RNA |
21798951 |
3.24Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3M4O |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex B |
20448203 |
3.57Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
C7P[ cis-diammine(pyridine)chloroplatinum(II) ] ZN MG |
| 3S17 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 9-nt RNA |
21798951 |
3.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S1M |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA (variant 1) |
21798951 |
3.13Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S1N |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA (variant 2) |
21798951 |
3.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S1Q |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt 3-deoxy RNA soaked with ATP |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ATP ZN MG |
| 3S1R |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt 3-deoxy RNA soaked with GTP |
21798951 |
3.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
GTP ZN MG |
| 3S2D |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA containing a 5Br-U |
21798951 |
3.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S2H |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 6-nt RNA containing a 2[prime]-iodo ATP |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4GWQ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Structure of the mediator head module from S. Cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA polymerase II RPB1 subunit |
23071300 |
4.50Å |
RNAP |
Mediator of RNA polymerase II transcription subunit 11,Mediator of RNA polymerase II transcription subunit 17,Mediator of RNA polymerase II transcription subunit 8,Mediator of RNA polymerase II transcription subunit 22,Mediator of RNA polymerase II transcription subuni p18,Mediator of RNA polymerase II transcription subunit 20,Mediator of RNA polymerase II transcription subunit 6,RPB1 |
|
| 4V1M |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Architecture of the RNA polymerase II-mediator core transcription initiation complex |
25652824 |
6.60Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4X67 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of elongating yeast RNA polymerase II stalled at oxidative cyclopurine DNA lesions. |
25605892 |
4.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 4X6A |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of yeast RNA polymerase II encountering oxidative cyclopurine DNA lesions |
25605892 |
3.96Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 4Y52 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of 5-carboxycytosine recognition by RNA polymerase II during transcription elongation. |
26123024 |
3.50Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4Y7N |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
The structure insight into 5-carboxycytosine recognition by RNA polymerase II during transcription elongation. |
26123024 |
3.30Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 5C4J |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5LVF |
SOLUTIONNMR |
Eukaryote |
Saccharomyces cerevisiae |
Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide |
28468956 |
|
CTD |
Regulator of Ty1 transposition protein 103 |
|
| 5M9D |
SOLUTIONNMR |
Eukaryote |
Saccharomyces cerevisiae |
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2ser7 phosphorylated CTD peptide |
29073019 |
|
CTD |
Regulator of Ty1 transposition protein 103 |
|
| 5VKL |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
SPT6 tSH2-RPB1 1476-1500 Ps1493 |
28826505 |
2.20Å |
TF |
Transcription elongation factor SPT6,RPB1 |
|
| 5VKO |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
SPT6 tSH2-RPB1 1468-1500 pT1471, Ps1493 |
28826505 |
1.80Å |
TF |
Transcription elongation factor SPT6,RPB1 |
IPO[ ISOPROPYL ALCOHOL ] |
| 5W4U |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Pol II elongation complex with an N6-methyladenine-containing template |
28933854 |
3.60Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5W51 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Pol II elongation complex with an n6-methyladenine-containing template and a matched UMPNPP |
28933854 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
2KH[ 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine ] ZN MG |
| 6BLO |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I+1 position |
29487211 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6BLP |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I+1 position, soaking AMPCPP |
29487211 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[[DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 6BM2 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I-1 position |
29487211 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6BM4 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I-1 position,soaking UMPNPP |
29487211 |
2.95Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
2KH[ 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine ] ZN MG |
| 6BQF |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Pol II elongation complex with dt-apat I+1, I-1 position |
29487211 |
3.35Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6NPW |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Ssu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide |
30971428 |
2.49Å |
RNAP |
Symplekin,Ssu72 ortholog(LD40846p),Ser2/Ser5 phosphorylated peptide |
PO4 |
| 6O6C |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex arrested at a CPD lesion |
31200019 |
3.10Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UPX |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1 |
32284409 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UPY |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2e |
32284409 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 6UPZ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3 |
32284409 |
3.10Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
PPV[ PYROPHOSPHATE ] ZN MG |
| 6UQ0 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 4 |
32284409 |
3.56Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UQ2 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with Dg in state 1 |
32284409 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UQ1 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6 |
32284409 |
3.60Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UQ3 |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5 |
32284409 |
3.47Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
PPV[ PYROPHOSPHATE ] ZN MG |
| 3GTO |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 15mer RNA |
19478184 |
4.00 Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2CKZ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
X-ray structure of RNA polymerase III subcomplex C17-C25. |
16818233 |
3.20Å |
RNAP |
RNAPIII 18KD polypeptide,RNAPIII 25KD polypeptide |
|
| 1DZF |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RPB5 from S.cerevisiae
|
10841537 |
1.90Å |
RNAP |
RPABC1 |
|
| 7KED |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with unnatural base dTPT3 |
34140682 |
3.60Å |
EM |
RNAP |
ZN,MG |
| 7KEE |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site |
34140682 |
3.45Å |
EM |
RNAP |
WCG [insert into `user` values (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol],ZN,MG |
| 7KEF |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state |
34140682 |
3.89Å |
EM |
RNAP |
WCG [insert into `user` values (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol],ZN,MG |
| 7RIQ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex scaffold 1 without polyamide |
35022237 |
3.00Å |
EM |
RNAP |
ZN,MG |
| 7RIM |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 |
35022237 |
2.90Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIQ |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 soaked with CTP
|
35022237 |
3.30Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIW |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex scaffold 2, without polyamide
|
35022237 |
3.20Å |
EM |
RNAP |
ZN,MG |
| 7RIX |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2
|
35022237 |
3.40Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIP |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 soaked with CTP
|
35022237 |
3.30Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIY |
XRD |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2 soaked with UTP
|
35022237 |
3.70Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7ML4 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initially transcribing complex (ITC) |
35051353 |
3.10Å |
IC |
RNAP,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIB,BJ4_G0050160.mRNA.1.CDS.1,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH,Tfb1,General transcription and DNA repair factor IIH helicase subunit XPB,General transcription and DNA repair factor IIH subunit TFB5,RNA polymerase II transcription factor B subunit 2,Transcription initiation factor IIE subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,TATA-box-binding protein,Transcription initiation factor IIE subunit alpha |
SF4,MG,ZN |
| 7MEI |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Composite structure of EC+EC |
35051353 |
3.54Å |
EC |
RNAP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta |
MG,ZN |
| 7MK9 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Complex structure of trailing EC of EC+EC (trailing EC-focused) |
35051353 |
3.54Å |
EC |
RNAP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta |
MG,ZN |
| 7MKA |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Complex structure of trailing EC of EC+EC (trailing EC-focused) |
35051353 |
3.54Å |
EC |
RNAP |
MG,ZN |
| 7ML1 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II pre-initiation complex (PIC2) |
35051353 |
4.00Å |
PIC |
RNAP,Tfb1,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit SSL1,RNA polymerase II transcription factor B subunit 2,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH helicase subunit XPB,BJ4_G0050160.mRNA.1.CDS.1,TATA-box-binding protein,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta |
SF4,MG,ZN |
| 7ML2 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II pre-initiation complex (PIC3) |
35051353 |
3.40Å |
PIC |
RNAP,Tfb1,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,BJ4_G0004860.mRNA.1.CDS.1,Tfb1,Tfb4,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH,RNA polymerase II transcription factor B subunit 2,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH helicase subunit XPB,BJ4_G0050160.mRNA.1.CDS.1 |
SF4,MG,ZN |
| 7ML4 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II initially transcribing complex (ITC) |
35051353 |
3.10Å |
PIC |
RNAP,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIB,BJ4_G0050160.mRNA.1.CDS.1,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH,Tfb1,General transcription and DNA repair factor IIH helicase subunit XPB,General transcription and DNA repair factor IIH subunit TFB5,RNA polymerase II transcription factor B subunit 2,Transcription initiation factor IIE subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,TATA-box-binding protein,Transcription initiation factor IIE subunit alpha |
SF4,MG,ZN |
| 7O4I |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble |
34133942 |
3.20Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O4J |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex (consensus) |
34133942 |
2.90Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O4K |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast TFIIH in the contracted state within the pre-initiation complex |
34133942 |
3.60Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O4L |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast TFIIH in the expanded state within the pre-initiation complex |
34133942 |
3.40Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O72 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA |
34133942 |
3.40Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O73 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA |
34133942 |
3.40Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB2,subunit TFB1,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O75 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA |
34133942 |
3.20Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB2,subunit TFB1,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7ML0 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
RNA polymerase II pre-initiation complex (PIC1) |
35051353 |
3.00Å |
PIC |
RNAP,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,TATA-box-binding protein,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit SSL1,RNA polymerase II transcription factor B subunit 2,General transcription and DNA repair factor IIH subunit TFB5,BJ4_G0050160.mRNA.1.CDS.1,General transcription and DNA repair factor IIH helicase subunit XPB |
SF4,MG,ZN |
| 7UIG |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Mediator-PIC Early (Mediator A) |
36731470 |
4.30 Å |
PIC |
Mediator of RNA polymerase II transcription subunit 1,subunit 4,subunit 6,subunit 7,subunit 8,subunit 9,subunit 10,subunit 11,subunit 14, subunit 17,subunit 18,subunit 19,subunit 20,subunit 21,subunit 22,subunit 31,DNA-directed RNA polymerase II subunit RPB1 |
|
| 7MKA |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of EC+EC (leading EC-focused) |
|
3.54 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC5,RPABC4 |
ZN,MG |
| 7MEI |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Composite structure of EC+EC |
35051353 |
3.54 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,DNA-directed RNA polymerase II subunit RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta |
ZN,MG |
| 7MK9 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Complex structure of trailing EC of EC+EC (trailing EC-focused) |
|
3.54 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta |
ZN,MG |
| 8CEN |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator |
37014863 |
3.00 Å |
PIC |
General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,TATA-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,Mediator of RNA polymerase II transcription subunit 6,Mediator of RNA polymerase II transcription subunit 8,Mediator of RNA polymerase II transcription subunit 11,Mediator of RNA polymerase II transcription subunit 17,Mediator of RNA polymerase II transcription subunit 18,Mediator of RNA polymerase II transcription subunit 20,Mediator of RNA polymerase II transcription subunit 22,Mediator of RNA polymerase II transcription subunit 4,Mediator of RNA polymerase II transcription subunit 7,Mediator of RNA polymerase II transcription subunit 9,Mediator of RNA polymerase II transcrip |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 8CEO |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome |
37014863 |
3.60 Å |
PIC |
General transcription and DNA repair factor IIH helicase subunit XPD,TFB1 isoform 1,RNA polymerase II transcription factor B subunit 2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH,General transcription and DNA repair factor IIH helicase subunit XPB,RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC5,RPABC4,Transcription initiation factor IIB,TATA-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,TOA1 isoform 1,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,Mediator of RNA polymerase II transcription subunit 1,4,6,7,8,9,10,11,14,17,18,19,20,21,22,31,Histone H3.2,Histone H4,Histone H2A,Histone H2B |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 7UIL |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Mediator-PIC Early (Tail A/B Dimer) |
36731470 |
4.30 Å |
PIC |
Mediator of RNA polymerase II transcription subunit 1,2,3,5,14,15,16 |
|
| 7ZS9 |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) |
36411341 |
3.10 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 7ZSA |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B) |
36411341 |
4.00 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 7ZSB |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C |
36411341 |
6.60 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 7Z0O |
EM |
Eukaryote |
Saccharomyces cerevisiae |
Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA |
35442737 |
2.80 Å |
RNAP |
Histone H3,Histone H4,RNA polymerase I-specific transcription initiation factor RRN5,RNA polymerase I-specific transcription initiation factor RRN9,RNA polymerase I-specific transcription initiation factor RRN10,Upstream activation factor subunit UAF30,TATA-box-binding protein |
|
| 6YMW |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex |
33278362 |
3.71 Å |
IC |
Mitochondrial transcription factor 1,DNA-directed RNA polymerase, mitochondrial |
P5E[ [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl] phosphono hydrogen phosphate ] MG |
| 6YMV |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Cryo-EM structure of yeast mitochondrial RNA polymerase partially-melted transcription initiation complex (PmIC) |
33278362 |
3.10Å |
IC |
Mitochondrial transcription factor 1,DNA-directed RNA polymerase, mitochondrial |
|
| 8BWS |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Structure of yeast RNA Polymerase III elongation complex at 3.3 A |
36977686 |
3.20 Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPABC5,RPAC2,RPABC4,RPC3,RPC6,RPC7 |
4QM[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol],ZN,MG |
| 7Z2Z |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A |
36977686 |
3.07 Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPABC5,RPAC2,RPABC4,RPC3,RPC6,RPC7,Integrase, |
4QM[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol],ZN,MG |
| 7Z0H |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40). |
36977686 |
2.60 Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPABC5,RPAC2,RPABC4,RPC3,RPC6,RPC7,Integrase, |
ZN,MG |
| 7Z30 |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11 terminal Zn-ribbon in the funnel pore). |
36977686 |
2.90 Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPABC5,RPAC2,RPABC4,RPC3,RPC6,RPC7,Integrase, |
ZN,MG |
| 7Z31 |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore). |
36977686 |
2.76 Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPABC5,RPAC2,RPABC4,RPC3,RPC6,RPC7,Integrase, |
ZN,MG |
| 7UI9 |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Core Mediator-PICearly (Copy A) |
36731470 |
3.30 Å |
|
Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription elongation factor S-II,Mediator of RNA polymerase II transcription subunit 1,Mediator of RNA polymerase II transcription subunit 4,Mediator of RNA polymerase II transcription subunit 6,Mediator of RNA polymerase II transcription subunit 7,Mediator of RNA polymerase II transcription subunit 8,Mediator of RNA polymerase II transcription subunit 9,Mediator of RNA polymerase II transcription subunit 10,Mediator of RNA polymerase II transcription subunit 11,Mediator of RNA polymerase II transcription subunit 14,Mediator of RNA polymerase II transcription subunit 17,Mediator of RNA polymerase II transcription subunit 18,Mediator of RNA polymerase II transcription subunit 19,Mediator of RNA polymerase II transcription subunit 20,Mediator of RNA polymerase II transcription subunit 21,Mediator of RNA polymerase II transcription subunit 22,Mediator of RNA polymerase II transcription subunit 31,RPB1,RPB2,RPB3,RPB4,RPABC1,RPABC2,RPB7,RPABC3,RPB9,RPABC5,RPB11,RPABC4 |
|
| 7UIO |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Mediator-PIC Early (Composite Model) |
36731470 |
3.30 Å |
PIC |
Mediator of RNA polymerase II transcription subunit 15,1,2,3,4,6,7,8,9,10,11,14,5,16,17,18,19,20,21,22,31,Regulatory protein GAL4,RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription elongation factor S-II |
ASP[ASPARTIC ACID],THR[THREONINE],ALA[ALANINE],ZN |
| 7UIF |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Mediator-PIC Early (Core B) |
36731470 |
4.60 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription elongation factor S-II,Mediator of RNA polymerase II transcription subunit 1,4,6,7,8,9,10,11,14,17,18,19,20,21,22,31 |
|
| 7UIC |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Mediator-PIC Early (Tail A) |
36731470 |
3.70 Å |
PIC |
Mediator of RNA polymerase II transcription subunit 2,3,5,14,15,16 |
|
| 7UIK |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Mediator-PIC Early (Tail A + Upstream DNA & Activator) |
36731470 |
7.70 Å |
PIC |
Regulatory protein GAL4,Mediator of RNA polymerase II transcription subunit 2,3,5,14,15,16, |
ZN |
| 7O3D |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Cooperation between the intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly |
35640611 |
3.71 Å |
Domain |
Transcription elongation factor SPT6 |
|
| 7O3D |
EM |
Eukaryote |
Saccharomyces cerevisiae S288C |
Cooperation between the intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly |
35640611 |
3.71 Å |
Domain |
Transcription elongation factor SPT6 |
|
| 7Z1L |
EM |
Eukaryote |
Saccharomyces cerevisiae W303 |
Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC) |
36070694 |
2.80 Å |
PTC |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
4QM[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol],ZN,MG |
| 7Z1O |
EM |
Eukaryote |
Saccharomyces cerevisiae W303 |
Structure of yeast RNA Polymerase III PTC + NTPs |
36070694 |
2.70 Å |
PTC |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
1N7[CHAPSO], ZN,MG |
| 7Z1M |
EM |
Eukaryote |
Saccharomyces cerevisiae W303 |
Structure of yeast RNA Polymerase III Elongation Complex (EC) |
36070694 |
3.40 Å |
EC |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPC10,RPABC5,RPAC2,RPABC4,RPC5,RPC4,RPC3,RPC6,RPC7 |
4QM[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol],ZN,MG |
| 7Z1N |
EM |
Eukaryote |
Saccharomyces cerevisiae W303 |
Structure of yeast RNA Polymerase III Delta C53-C37-C11 |
36070694 |
3.90 Å |
RNAP |
RPC1,RPC2,RPAC1,RPC9,RPABC1,RPABC2,RPC8,RPABC3,RPABC5,RPAC2,RPABC4,RPC3,RPC6,RPC7 |
1N7[CHAPSO], ZN,MG |
| 7NKY |
EM |
Eukaryote |
Saccharomyces cerevisiae, Xenopus laevis |
RNA Polymerase II-Spt4/5-nucleosome-FACT structure |
33846633 |
3.20Å |
RNAP |
RNAP,Chromatin elongation factor SPT4,Transcription elongation factor SPT5,FACT complex subunit POB3,FACT complex subunit SPT16,Histone H3.2,Histone H4,Histone H2A type 1,Histone H2B 1.1 |
MG,ZN |
| 7NKX |
EM |
Eukaryote |
Saccharomyces cerevisiae, Xenopus laevis |
RNA polymerase II-Spt4/5-nucleosome-Chd1 structure |
33846633 |
2.90Å |
RNAP |
RNAP,Histone H3.2,Histone H4,Histone H2A type 1,Histone H2B 1.1,Chromo domain-containing protein 1,Chromatin elongation factor SPT4,Chromatin elongation factor SPT5 |
ADP,BEF,MG,ZN |
| 7AOE |
EM |
Eukaryote |
Schizosaccharomyces pombe |
Schizosaccharomyces pombe RNA polymerase I (elongation complex) |
33536435 |
3.90Å |
EM |
RNAP |
ZN |
| 3H0G |
XRD |
Eukaryote |
Schizosaccharomyces pombe |
RNA polymerase II from schizosaccharomyces pombe |
19458260 |
3.65 Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4PZ6 |
XRD |
Eukaryote |
Schizosaccharomyces pombe |
PCE1 guanylyltransferase bound to Ser2/Ser5 phosphorylated RNA pol II CTD |
24939935 |
2.41Å |
RNAP |
mRNA-capping enzyme subunit alpha, RPB1 |
GMP |
| 5U0S |
EM |
Eukaryote |
Schizosaccharomyces pombe |
Cryo-EM structure of the mediator-RNAPII complex |
28241144 |
7.80Å |
RNAP |
Mediator complex subunit 6,Mediator complex subunit 8,Mediator complex subunit 17,Mediator complex subunit 18,Mediator complex subunit 20,Mediator complex subunit 11,Mediator complex subunit 22,Mediator complex subunit 14,Mediator complex subunit 4,Mediator complex subunit 7,Mediator complex subunit 21,Mediator complex subunit 31,Mediator complex subunit 27,Mediator complex subunit 9,Mediator complex subunit 19,Mediator complex subunit 10,RPB1, RPB2,RPB3,RPB4, RPB5,RPB6,RPB7,RPB8,RPB9,RPB10, RPB11,RPB12 |
|
| 7AOD |
EM |
Eukaryote |
Schizosaccharomyces pombe |
Schizosaccharomyces pombe RNA polymerase I (dimer) |
33536435 |
4.50Å |
RNAP |
RNAP |
ZN |
| 6EXV |
EM |
Eukaryote |
Sus scrofa |
Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin |
29550768 |
3.60 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 6GMH |
EM |
Eukaryote |
Sus scrofa |
Structure of activated transcription complex pol II-DSIF-paf-SPT6 |
30135578 |
3.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,SPT6,CTR9,LEO1,PAF1,WD repeat-containing protein 61,CDC73,Spt4,Spt5 |
ZN MG |
| 6GML |
EM |
Eukaryote |
Sus scrofa |
Structure of paused transcription complex pol II-DSIF-NELF |
30135580 |
3.20Å |
EC |
DNA-directed RNA polymerase subunit,beta,C,E,F,RPABC3,RPB9,Negative elongation factor A,Negative elongation factor B,Negative elongation factor C/D,Negative elongation factor E,Spt4,Spt5,D,G |
ZN MG |
| 6TED |
EM |
Eukaryote |
Sus scrofa |
Structure of complete, activated transcription complex pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 |
32541898 |
3.10 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,CTR9 homolog, RTF1 homolog,LEO1,RAF1,WD repeat-containing protein 61,Spt4/5/6 |
ZN MG |
| 7OZP |
EM |
Eukaryote |
Sus scrofa domesticus |
RNA Polymerase II dimer (Class 3)
|
34530439 |
3.80Å |
RNAP |
RNAP |
ZN |
| 7OZN |
EM |
Eukaryote |
Sus scrofa domesticus |
RNA Polymerase II dimer (Class 1)
|
34530439 |
3.50Å |
RNAP |
RNAP |
ZN |
| 7OZO |
EM |
Eukaryote |
Sus scrofa domesticus |
RNA Polymerase II dimer (Class 2)
|
34530439 |
3.80Å |
RNAP |
RNAP |
ZN |
| 7B7U |
EM |
Eukaryote |
Sus scrofa domesticus, Homo sapiens |
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 |
34021257 |
2.80Å |
RNAP |
RNAP |
ZN |
| 7NVU |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
RNA polymerase II core pre-initiation complex with open promoter DNA |
33902107 |
2.50Å |
PIC |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,subunit 1,General transcription factor IIE subunit 1,subunit beta |
MG,ZN |
| 7NVU |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
RNA polymerase II core pre-initiation complex with open promoter DNA |
33902107 |
2.50Å |
PIC |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,subunit 1,General transcription factor IIE subunit 1,subunit beta |
MG,ZN |
| 7NVZ |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
RNA polymerase II pre-initiation complex with closed promoter DNA in distal position |
33902107 |
7.20Å |
PIC |
TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,subunit 4,subunit 3,subunit 5,subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,CDK-activating kinase assembly factor MAT1,RNAP,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,subunit 2,Transcription initiation factor IIA subunit 1,General transcription factor IIE subunit 1,subunit beta |
SF4,MG,ZN |
| 7F4G |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Structure of RPAP2-bound RNA polymerase II |
35476980 |
2.78Å |
RNAP |
RNAP |
ZN |
| 7NVY |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position |
33902107 |
7.30Å |
PIC |
TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,subunit 4,subunit 3,subunit 5,subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,CDK-activating kinase assembly factor MAT1,RNAP,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,subunit 2,Transcription initiation factor IIA subunit 1,General transcription factor IIE subunit 1,subunit beta,CDK-activating kinase assembly factor MAT1 |
SF4,MG,ZN |
| 7NW0 |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
RNA polymerase II pre-initiation complex with open promoter DNA |
33902107 |
6.60Å |
PIC |
TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,subunit 4,subunit 3,subunit 5,subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,CDK-activating kinase assembly factor MAT1,RNAP,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,subunit 2,Transcription initiation factor IIA subunit 1,General transcription factor IIE subunit 1,subunit beta,CDK-activating kinase assembly factor MAT1 |
ADP,BEF,SF4,MG,ZN |
| 7B0Y |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Structure of a transcribing RNA polymerase II-U1 snRNP complex |
33446560 |
3.60Å |
RNAP |
RNAP,U1 small nuclear ribonucleoprotein 70 kDa,U1 small nuclear ribonucleoprotein A,Small nuclear ribonucleoprotein Sm D2,Small nuclear ribonucleoprotein F,Small nuclear ribonucleoprotein E,Small nuclear ribonucleoprotein G,Small nuclear ribonucleoprotein Sm D3,Small nuclear ribonucleoprotein-associated protein,Small nuclear ribonucleoprotein Sm D1 |
MG,ZN |
| 7OO3 |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Pol II-CSB-CSA-DDB1-UVSSA (Structure1) |
34526721 |
2.80Å |
RNAP |
RNAP,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,CSB element,UV-stimulated scaffold protein A,DNA damage-binding protein 1 |
ZN,MG |
| 7OOB |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) |
34526721 |
2.70Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,DNA excision repair protein ERCC-6,DNA damage-binding protein 1,DNA excision repair protein ERCC-8 |
ADP,BEF,ZN,MG |
| 7OOP |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) |
34526721 |
2.90Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription elongation factor SPT6,LEO1 helix,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WD repeat-containing protein 61,Parafibromin,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,UV-stimulated scaffold protein A,DNA damage-binding protein 1 |
ZN,MG |
| 7OPC |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) |
34526721 |
3.00Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription elongation factor SPT6,LEO1 helix,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WD repeat-containing protein 61,Parafibromin,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,UV-stimulated scaffold protein A,DNA damage-binding protein 1,Cullin-4A,E3 ubiquitin-protein ligase RBX1 |
ZN,MG |
| 7OPD |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) |
34526721 |
3.00Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription elongation factor SPT6,LEO1 helix,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WD repeat-containing protein 61,Parafibromin,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,UV-stimulated scaffold protein A,DNA damage-binding protein 1,Cullin-4A,E3 ubiquitin-protein ligase RBX1 |
ZN,MG |
| 8BZ1 |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) |
37148879 |
3.80 Å |
PIC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPB11-a,RPABC3,RPABC5,RNA polymerase II subunit D,DNA-directed RNA polymerase II subunit E,F,RNA polymerase II subunit K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,Histone H3.2,Histone H4,Histone H2A type 1,Histone H2B 1.1 |
ZN,MG |
| 7ZWD |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) |
36424526 |
3.00 Å |
PIC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RNA polymerase II subunit D,E,F,J,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,snRNA-activating protein complex subunit 1,snRNA-activating protein complex subunit 3,snRNA-activating protein complex subunit 4,snRNA-activating protein complex subunit 5 |
ZN,MG |
| 7ZX7 |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) |
36424526 |
3.40 Å |
PIC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RNA polymerase II subunit D,E,F,J,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,snRNA-activating protein complex subunit 1,snRNA-activating protein complex subunit 3,snRNA-activating protein complex subunit 4,snRNA-activating protein complex subunit 5 |
ZN,MG |
| 7ZX8 |
EM |
Eukaryote |
Sus scrofa, Homo sapiens |
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) |
36424526 |
3.00 Å |
PIC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RNA polymerase II subunit D,E,F,J,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,snRNA-activating protein complex subunit 1,snRNA-activating protein complex subunit 3,snRNA-activating protein complex subunit 4,snRNA-activating protein complex subunit 5 |
ZN,MG |
| 7OL0 |
EM |
Eukaryote |
Sus scrofa, Homo sapiens, HIV whole-genome vector AA1305#18 |
Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) |
34265249 |
3.00Å |
EC |
RNAP,Transcription elongation factor SPT5 |
ZN,MG |
| 7OKX |
EM |
Eukaryote |
Sus scrofa, Homo sapiens, HIV whole-genome vector AA1305#18 |
Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure) |
34265249 |
3.30Å |
EC |
RNAP,RNA polymerase II elongation factor ELL2,ELL-associated factor 1,Transcription elongation factor SPT5 |
ZN,MG |
| 7OKY |
EM |
Eukaryote |
Sus scrofa, Homo sapiens, HIV whole-genome vector AA1305#18 |
Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) |
34265249 |
4.14Å |
EC |
RNAP,RNA polymerase II elongation factor ELL2,ELL-associated factor 1,Transcription elongation factor SPT5,Transcription elongation factor SPT5 |
ZN,MG |
| 7UND |
EM |
Eukaryote |
Sus scrofa, Homo sapiens, Xenopus laevis |
Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) |
35709268 |
3.00 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB8,RPB9,RPB10,RPB11,RPOL4c domain-containing protein,DNA-directed RNA polymerase II subunit E,RPABC2,RNA polymerase II subunit K,Transcription elongation factor SPT6,Transcription elongation factor A protein 1,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein RTF1 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WDR61,Parafibromin,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
ZN,MG |
| 7UNC |
EM |
Eukaryote |
Sus scrofa, Homo sapiens,Xenopus laevis |
Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome |
35709268 |
3.00 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB8,RPB9,RPB10,RPB11,RPOL4c domain-containing protein,DNA-directed RNA polymerase II subunit E,RPABC2,RNA polymerase II subunit K,Transcription elongation factor SPT6,Transcription elongation factor A protein 1,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein RTF1 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WDR61,Parafibromin,Transcription elongation factor SPT5,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
ZN,MG |
| 8H02 |
XRD |
Eukaryote |
Synechococcus elongatus PCC 7942 = FACHB-805 |
Crystal structure of Synechococcus elongatus PCC 7942 RNA polymerase SI3-tail |
|
1.55 Å |
RNAP |
DNA-directed RNA polymerase subunit beta' |
|
| 8GZG |
EM |
Eukaryote |
Synechocystis sp. PCC 6803 |
Cryo-EM structure of Synechocystis sp. PCC 6803 RPitc |
|
3.13 Å |
RNAP |
DNA-directed RNA polymerase subunit alpha,beta,beta',gamma,omega,RNA polymerase sigma factor SigA |
ZN,MG |
| 8GZH |
EM |
Eukaryote |
Synechocystis sp. PCC 6803 |
Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc |
|
2.96 Å |
RNAP |
DNA-directed RNA polymerase subunit alpha,beta,beta',gamma,omega,RNA polymerase sigma factor SigA |
CTP[CYTIDINE-5'-TRIPHOSPHATE],ZN,MG |
| 7AOF |
EM |
Eukaryote |
Vaccinia virus GLV-1h68 |
Atomic structure of the poxvirus transcription late pre-initiation complex |
34556871 |
2.98Å |
IC |
RNAP |
ZN,MG |