The small-molecule RNAP inhibitors of CVB3:


The structures of all RNA polymerases are superimposed, and the pockets where the inhibitors bind intensively are found and numbered pocket 1, pocket 2, pocket 3, etc. A table of inhibitors in each pocket, including inhibitor name, drug name, 2D structure, and 3D visualization.The ID and PDB are linked to PDB database.

Pocket ID PDB Name Drug 2D Diagram 3D Interaction
Pocket 45Z 4Y34 2,2'-[4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile)
1FS 4Y2A 2,2'-[4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile)