The small-molecule RNAP inhibitors of SARS-CoV-2：
The structures of all RNA polymerases are superimposed, and the pockets where the inhibitors bind intensively are found and numbered pocket 1, pocket 2, pocket 3, etc. A table of inhibitors in each pocket, including inhibitor name, drug name, 2D structure, and 3D visualization.The ID and PDB are linked to PDB database.
| ID | PDB | Name | Drug | 2D Diagram | 3D Interaction | |
|---|---|---|---|---|---|---|
| 1RP | 7DFG | 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide | Favipiravir-RMP |
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| 16B | 7OZV | 8-(3-(3-aminobenzamido)-4-methylbenzamido)naphthalene-1,3,5-trisulfonic acid | Suramin |
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| H3U | 7D4F | 8-(3-(3-aminobenzamido)-4-methylbenzamido)naphthalene-1,3,5-trisulfonic acid | Suramin |
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| F86 | 7BV2 | 8-(3-(3-aminobenzamido)-4-methylbenzamido)naphthalene-1,3,5-trisulfonic acid | Suramin |
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