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PDB	Method	Taxonomy	Organism	Name	Reference_pub	Resolution	Stage	Contents	Ligands
5UH5	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA	28392175	3.75 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	ZN MG
5UH6	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with rifampin	28392175	3.84 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	RFP[ RIFAMPICIN ],ZN,MG
5UH8	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA	28392175	4.18 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	ZN MG
5UH9	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA	28392175	4.40 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	ZN MG
5UHA	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex	28392175	3.91 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	ZN MG
5UHB	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with rifampin	28392175	4.29 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	RFP[ RIFAMPICIN ],ZN,MG
5UHC	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with rifampin	28392175	3.80 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	RFP[ RIFAMPICIN ],ZN,MG
5UHD	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA in complex with rifampin	28392175	4.01 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	RFP[ RIFAMPICIN ],ZN,MG
5UHE	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-APP1	28392175	4.04 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	88G[ Nalpha-(benzenecarbonyl)-N-(2-methylphenyl)-D-phenylalaninamide ],ZN,MG
5UHF	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-IX336	28392175	4.34 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	88D[ N-(2-methylphenyl)-Nalpha-(selenophene-2-carbonyl)-D-phenylalaninamide ],ZN,MG
5UHG	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-APP1 and rifampin	28392175	3.97 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	88G[ Nalpha-(benzenecarbonyl)-N-(2-methylphenyl)-D-phenylalaninamide ], RFP[RIFAMPICIN],ZN,MG
5ZX2	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA	30858373	2.80 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	ZN
5ZX3	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H	30858373	2.75 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	ZN
6BZO	EM	Prokaryote	Mycobacterium tuberculosis	Mtb RNAP holo/RbpA/fidaxomicin/upstream fork DNA	29480804	3.38 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA	FI8[ Fidaxomicin ],ZN,MG
6C04	EM	Prokaryote	Mycobacterium tuberculosis	Mtb RNAP holo/RbpA/double fork DNA -closed clamp	29480804	3.27 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA	ZN MG
6C05	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP holo/RbpA in relaxed state	29480804	5.15 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA	ZN MG
6C06	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP holo/RbpA/fidaxomicin	29480804	5.15 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA	FI8[ Fidaxomicin ],ZN,MG
6DV9	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor l) containing 5nt RNA with 4nt spacer	30755604	3.80 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor sig L	ZN MG
6DVB	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor l) containing 5nt RNA with 5nt spacer	30755604	3.80 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor sig L	ZN
6DVC	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor l) containing 5nt RNA with 6nt spacer	30755604	3.30 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor sig L	ZN
6DVD	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor l) with 6 nt spacer and bromine labelled in position '-11	30755604	3.90 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor sig L	ZN
6DVE	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ecf selenomethionine-labelled sigma factor l) with 6 nt spacer	30755604	3.81 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor sig L	ZN
6EDT	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP open promoter complex with RbpA/Card and AP3 promoter	30626968		IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA,RNA polymerase-binding transcription factor CarD	ZN MG
6EE8	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/Card and AP3 promoter	30626968	3.92 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA,RNA polymerase-binding transcription factor CarD	ZN MG
6EEC	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/Card and AP3 promoter captured by corallopyronin	30626968	3.55 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA,RNA polymerase-binding transcription factor CarD	C0L[ methyl [(1E,5R)-5-{(3E)-3-[(2E,4E,8R,9E,12E)-1,8-dihydroxy-2,5,9-trimethyltetradeca-2,4,9,12-tetraen-1-ylidene]-2,4-dioxo-3,4-d ihydro-2H-pyran-6-yl}hex-1-en-1-yl]carbamate ],ZN,MG
6FBV	XRD	Prokaryote	Mycobacterium tuberculosis	Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with fidaxomicin	29606590	3.52 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA	FI8[ Fidaxomicin ],ZN,MG
6JCX	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA	31131408	2.90 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigH	ZN MG
6JCY	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E	31131408	3.11 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigH	ZN MG
6KON	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 5 nt	32127479	3.00 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigH	ZN MG
6KOO	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 7 nt	32127479	2.80 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigH	ZN MG
6TYG	EM	Prokaryote	Mycobacterium tuberculosis	Crystal structure of MTB sigma L transcription initiation complex with 9 nt long RNA primer	32127479	3.50 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor
6KOP	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 9 nt	32127479	3.30 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigH	ZN MG
6KOQ	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 10 nt	32127479	3.35 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigH	ZN MG
6TYE	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer	32127479	3.79 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor
6TYF	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of MTB sigma L transcription initiation complex with 6 nt long RNA primer	32127479	3.80 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor
4KBJ	XRD	Prokaryote	Mycobacterium tuberculosis	Structure of MTB RNAP beta subunit B1 and B2 domains	24055315	2.45 Å	Subunit	DNA-directed RNA polymerase subunit beta
4KBM	XRD	Prokaryote	Mycobacterium tuberculosis	Structure of the MTB Card/RNAP beta subunit B1-B2 domains complex	24055315	2.11 Å	Subunit	DNA-directed RNA polymerase subunit beta,RNA polymerase-binding transcription factor CarD
4X8K	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RbpA-SID in complex with sigmaA domain 2	26040003	2.20 Å	Subunit	RNA polymerase sigma factor SigA,RNA polymerase-binding protein RbpA	SO4,EDO[ 1,2-ETHANEDIOL ]
6M7J	XRD	Prokaryote	Mycobacterium tuberculosis	Ycobacterium tuberculosis RNAP with RbpA/us fork and corallopyronin	30626968	4.40 Å	RNAP	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RbpA	C0L[ methyl [(1E,5R)-5-{(3E)-3-[(2E,4E,8R,9E,12E)-1,8-dihydroxy-2,5,9-trimethyltetradeca-2,4,9,12-tetraen-1-ylidene]-2,4-dioxo-3,4-d ihydro-2H-pyran-6-yl}hex-1-en-1-yl]carbamate ],ZN,MG
6VW0	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP s456l mutant open promoter complex	33199626	3.59 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA	ZN MG
6VVY	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis wt RNAP transcription open promoter complex with sorangicin	33199626	3.42 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA,RNA polymerase-binding transcription factor CarD	SRN[ SORANGICIN A],MG,ZN
6VVX	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis wt RNAP transcription initiation intermediate structure with sorangicin	33199626	3.39 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA,RNA polymerase-binding transcription factor CarD	SRN[ SORANGICIN A ],MG,ZN
6VVZ	XRD	Prokaryote	Mycobacterium tuberculosis	Ycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with sorangicin	33199626	3.72 Å	IC	DNA-directed RNA polymerase subunit alpha/beta/beta'/omega/sigma factor SigA,RNA polymerase-binding protein RbpA,RNA polymerase-binding transcription factor CarD	SRN[ SORANGICIN A ],MG,ZN
6ONO	XRD	Prokaryote	Mycobacterium tuberculosis	Complex structure of Whib1 and region 4 of siga in C2221 space group	31807774	1.85 Å	Subunit	Transcription regulator Whib1,RNA polymerase sigma factor SigA	SF4,PEG[ DI(HYDROXYETHYL)ETHER ]
6ONU	XRD	Prokaryote	Mycobacterium tuberculosis	Complex structure of Whib1 and region 4 of siga in P21 space group.	31807774	1.85 Å	Subunit	Transcriptional regulator Whib1,RNA polymerase sigma factor SigA	SF4,PEG[ DI(HYDROXYETHYL)ETHER ]
5UH7	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of beta'MtbSI of Mycobacterium tuberculosis RNA polymerase	28392175	2.20 Å	Subunit	DNA-directed RNA polymerase subunit beta'
3HUG	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sig L	20184899	2.35 Å	Subunit	RNA polymerase sigma factor,PROBABLE CONSERVED MEMBRANE PROTEin	SO4 ZN
4NQW	XRD	Prokaryote	Mycobacterium tuberculosis	Structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor sigk in complex with the cytosolic domain of its cognate anti-sigma factor RskA	24699647	2.40 Å	Subunit	ECF RNA polymerase sigma factor sig K,Anti-sigma-K factor RskA	CD
5XE7	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor sig J	28934483	2.16 Å	Subunit	ECF RNA polymerase sigma factor sig J
3VFZ	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of -35 promoter binding domain of sigd of Mycobacterium tuberculosis	23314154	1.90 Å	Subunit	Probable RNA polymerase sigma-D factor
2O7G	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of the pribnow box recognition region of sig C from Mycobacterium tuberculosis	17145760	2.70 Å	Subunit	Probable RNA polymerase sigma-C factor	SO4
2O8X	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of the '-35 element' promoter recognition domain of Mycobacterium tuberculosis sig C	17145760	3.00 Å	Subunit	Probable RNA polymerase sigma-C factor	SO5
3VEP	XRD	Prokaryote	Mycobacterium tuberculosis	Crystal structure of sigd4 in complex with its negative regulator RsdA	23314154	2.50 Å	Subunit	Uncharacterized protein Rv3413c/MT3522,Probable RNA polymerase sigma-D factor	SO4
7KIN	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter	34171296	2.74Å	TC	RNAP,RNA polymerase-binding transcription factor CarD	ZN,MG
7KIF	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor	34171296	2.94Å	TC	RNAP,RNA polymerase-binding transcription factor CarD,Probable transcriptional regulator WhiB7	SF4,ZN,MG
7KIM	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor	34171296	3.38Å	TC	RNAP,RNA polymerase-binding transcription factor CarD,Probable transcriptional regulator WhiB7	SF4,ZN,MG
8E8M	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP paused elongation complex		3.13 Å	EC	DNA-directed RNA polymerase subunit alpha,beta,beta',omega	ZN,MG
8.00E+95	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP elongation complex		2.90 Å	EC	DNA-directed RNA polymerase subunit alpha,beta,beta',omega	ZN,MG
7ZF2	EM	Prokaryote	Mycobacterium tuberculosis	Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor		3.86 Å	RNAP	DNA-directed RNA polymerase subunit alpha,beta,beta',omega,RNA polymerase sigma factor SigB	ZN,MG
7RWI	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNA polymerase sigma L holoenzyme open promoter complex containing TNP-2198	35175750	3.70 Å	RNAP	DNA-directed RNA polymerase subunit alpha,beta,beta',omega,RNA polymerase sigma factor	7US[(3aM,9S,10bP,14S,15R,16S,17R,18R,19R,20S,21S,25R)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,
7U22	XRD	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7	36222275	3.87 Å	RNAP	DNA-directed RNA polymerase subunit alpha,beta,beta',omega,RNA polymerase sigma factor SigA	KYO[(9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl
8.00E+74	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor		2.94 Å	EC	DNA-directed RNA polymerase subunit alpha,beta,beta',omega,Transcription termination/antitermination protein NusG	ZN,MG
8.00E+82	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor		3.03 Å	EC	DNA-directed RNA polymerase subunit alpha,beta,beta',omega,Transcription termination/antitermination protein NusG	ZN,MG
8.00E+79	EM	Prokaryote	Mycobacterium tuberculosis	Mycobacterium tuberculosis RNAP paused elongation complex with Escherichia coli NusG transcription factor		3.71 Å	EC	DNA-directed RNA polymerase subunit alpha,beta,beta',omega,Transcription termination/antitermination protein NusG	ZN,MG
8CYF	XRD	Prokaryote	Mycobacterium tuberculosis	WhiB3 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA	37142222	2.44 Å	RNAP	Redox- and pH-responsive transcriptional regulator WhiB3,RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera,DNA-directed RNA polymerase subunit beta	SF4[ IRON/SULFUR CLUSTER],CAC[CACODYLATE ION]

RNAP3D