RNAP3D

PDB Method Taxonomy Organism Name Reference_pub Resolution Stage  Contents   Ligands 
6M71 XRD Virus SARS-COV-2 SARS-COV-2 RNAP in complex with cofactors 32277040 2.90 Å RNAP Nsp12,Nsp7,Nsp8
6YYT XRD Virus SARS-COV-2 Structure of replicating SARS-COV-2 polymerase 32438371 2.90 Å RNAP Nsp12,Nsp7,Nsp8 ZN
7BTF XRD Virus SARS-COV-2 SARS-COV-2 RNAP in complex with cofactors in reduced condition 32277040 2.95 Å RNAP Nsp12,Nsp7,Nsp8 ZN
7BV1 XRD Virus SARS-COV-2 cryo-EM structure of the apo nsp12-nsp7-nsp8 complex 32358203 2.80 Å RNAP Nsp12,Nsp7,Nsp8 ZN
7BV2 XRD Virus SARS-COV-2 The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of remdesivir(rtp) 32358203 2.50 Å RNAP Nsp12,Nsp7,Nsp8 F86[[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate] , POP[ PYROPHOSPHATE 2- ], ZN, MG
7BZF XRD Virus SARS-COV-2 Covid-19 RNAP post-translocated catalytic complex 32526208 3.26 Å RNAP Nsp12,Nsp7,Nsp8 ZN
7C2K XRD Virus SARS-COV-2 Covid-19 RNAP pre-translocated catalytic complex 32526208 2.93 Å RNAP Nsp12,Nsp7,Nsp8 ZN
7B3D XRD Virus SARS-COV-2 Structure of elongating SARS-COV-2 RNAP with AMP at position -4 (structure 3) 33436624 2.80 Å RNAP Nsp12,Nsp7,Nsp8 ZN
7AAP XRD Virus SARS-COV-2 Nsp7-nsp8-nsp12 SARS-COV2 RNAP in complex with template:primer dsRNA and favipiravir-rtp 33526596 2.50 Å RNAP Nsp12,Nsp7,Nsp8 GE6[[[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonyl-5-fluoranyl-2-oxidanylidene-pyrazin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate] , POP[ PYROPHOSPHATE 2- ], ZN, MG
7CTT XRD Virus SARS-COV-2 Cryo-EM structure of favipiravir bound to replicating polymerase complex of SARS-COV-2 in the pre-catalytic state. 33521757 3.20 Å RNAP Nsp12,Nsp7,Nsp8 GE6[[[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonyl-5-fluoranyl-2-oxidanylidene-pyrazin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate] , ZN, MG
6XQB XRD Virus SARS-COV-2 SARS-COV-2 RDRP/RNA complex To be published. 3.40 Å RNAP Nsp12,Nsp7,Nsp8 ZN, MG
7CXN XRD Virus SARS-COV-2 Architecture of a SARS-COV-2 mini replication and transcription complex 33208736 3.84 Å RNAP Nsp12,Nsp8,Nsp7,Helicase ZN
7CXM XRD Virus SARS-COV-2 Architecture of a SARS-COV-2 mini replication and transcription complex 33208736 2.90 Å RNAP Nsp12,Nsp8,Nsp7,Helicase ZN
7BW4 XRD Virus SARS-COV-2 Structure of the RNAP from SARS-COV-2 32531208 3.70 Å RNAP Nsp12,Nsp8,Nsp7 ZN
7B3C XRD Virus SARS-COV-2 Structure of elongating SARS-COV-2 RNAP with remdesivir at position -4 (structure 2) 33436624 3.40 Å RNAP Nsp12,Nsp8,Nsp7 ZN
7B3B XRD Virus SARS-COV-2 Structure of elongating SARS-COV-2 RNAP with remdesivir at position -3 (structure 1) 33436624 3.10 Å RNAP Nsp12,Nsp8,Nsp7 ZN
7D4F XRD Virus SARS-COV-2 Structure of covid-19 RNAP bound to suramin 33674802 2.57 Å RNAP Nsp12,Nsp8,Nsp7 H3U ??8-(3-(3-aminobenzamido)-4-methylbenzamido)naphthalene-1,3,5-trisulfonic acid?? Zn
7CYQ XRD Virus SARS-COV-2 Cryo-EM structure of an extended SARS-COV-2 replication and transcription complex reveals an intermediate state in cap synthesis 33232691 2.83 Å TC Nsp12,Nsp8,Nsp7,Helicase GDP ZN MG
6WTC XRD Virus SARS-COV-2 Crystal structure of the second form of the co-factor complex of nsp7 and the C-terminal domain of nsp8 from SARS-COV-2 To be published. 1.85 Å Subunit Nsp7,Nsp8 ACY [ ACETIC ACID ]
6WIQ XRD Virus SARS-COV-2 Crystal structure of the co-factor complex of nsp7 and the C-terminal domain of nsp8 from SARS-COV-2 34197805 2.85 Å Subunit Nsp7,Nsp8
6WQD XRD Virus SARS-COV-2 The 1.95 a crystal structure of the co-factor complex of nsp7 and the C-terminal domain of nsp8 from SARS-COV-2 34197805 1.95 Å Subunit Nsp7,Nsp8 EDO[ 1,2-ETHANEDIOL ]
6XIP XRD Virus SARS-COV-2 The 1.5 a crystal structure of the co-factor complex of nsp7 and the C-terminal domain of nsp8 from SARS-COV-2 34197805 1.50 Å Subunit Nsp7,Nsp8 EDO[ 1,2-ETHANEDIOL ]
7OZV EM Virus SARS-CoV-2 SARS-CoV-2 RdRp with Molnupiravir/ NHC in the template strand base-paired with G 34381216 3.20Å RNAP Replicase polyprotein 1ab,Non-structural protein 8,Non-structural protein 7 ZN
7OZU EM Virus SARS-CoV-2 SARS-CoV-2 RdRp with Molnupiravir/ NHC in the template strand base-paired with A 34381216 3.30Å RNAP Replicase polyprotein 1ab,Non-structural protein 8,Non-structural protein 7 ZN
7DFG EM Virus SARS-CoV-2 Structure of COVID-19 RNA-dependent RNA polymerase bound to favipiravir To be published 2.70Å RNAP RdRp,Non-structural protein 8,Non-structural protein 7 1RP[6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide],POP,ZN ,MG
7L1F EM Virus SARS-CoV-2 SARS-CoV-2 RdRp in complex with 4 Remdesivir monophosphate 33631104 3.89Å RNAP RdRp,Non-structural protein 8,Non-structural protein 7
7DOK EM Virus SARS-CoV-2 Structure of COVID-19 RNA-dependent RNA polymerase (extended conformation) bound to penciclovir To be published. 2.73Å RNAP RdRp,Non-structural protein 8,Non-structural protein 7 HCU[ [(2R)-4-(2-azanyl-6-oxidanylidene-3H-purin-9-yl)-2-(hydroxymethyl)butyl] dihydrogen phosphate ],POP[ PYROPHOSPHATE 2- ],ZN,MG
7DOI EM Virus SARS-CoV-2 Structure of COVID-19 RNA-dependent RNA polymerase bound to penciclovir. To be published. 2.60Å RNAP RdRp,Non-structural protein 8,Non-structural protein 7 HCU[ [(2R)-4-(2-azanyl-6-oxidanylidene-3H-purin-9-yl)-2-(hydroxymethyl)butyl] dihydrogen phosphate ],POP[ PYROPHOSPHATE 2- ],ZN,MG
7DFH EM Virus SARS-CoV-2 Structure of COVID-19 RNA-dependent RNA polymerase bound to ribavirin To be published. 2.97Å RNAP RdRp,Non-structural protein 8,Non-structural protein 7 RVP[ RIBAVIRIN MONOPHOSPHATE ] , POP[ PYROPHOSPHATE 2- ] ZN MG