| 5FLM |
EM |
Eukaryote |
RNAP II |
Bos taurus |
Structure of transcribing mammalian RNA polymerase II |
26789250 |
3.40 Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5OIK |
EM |
Eukaryote |
RNAP II |
Bos taurus |
Structure of an RNA polymerase II-DSIF transcription elongation complex |
28892040 |
3.70Å |
EC |
RNA polymerase II,Spt4,Spt5 |
ZN MG |
| 2GHQ |
XRD |
Eukaryote |
RNAP II |
Homo sapiens |
CTD-specific phosphatase SCP1 in complex with peptide C-terminal domain of RNA polymerase II |
17157258 |
2.05 Å |
RNAP |
RNAP II largest subunit,Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
MG |
| 2GHT |
XRD |
Eukaryote |
RNAP II |
Homo sapiens |
CTD-specific phosphatase SCP1 in complex with peptide from C-terminal domain of RNA polymerase II |
17157258 |
1.80 Å |
RNAP |
RNAP II largest subunit,Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
MG |
| 2LTO |
SOLUTIONNMR |
Eukaryote |
RNAP II |
Homo sapiens |
TDRD3 complex |
23066109 |
|
Subunit |
TDRD3,RPB1 |
|
| 5IY6 |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human holo-PIC in the closed state |
27193682 |
7.20 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IY7 |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human holo-PIC in the open state |
27193682 |
8.60 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IY8 |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human holo-PIC in the initial transcribing state |
27193682 |
7.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IY9 |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human holo-PIC in the initial transcribing state (no IIS) |
27193682 |
6.30 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1,TFIIH |
ZN MG |
| 5IYA |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human core-PIC in the closed state |
27193682 |
5.40 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1 |
ZN MG |
| 5IYB |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human core-PIC in the open state |
27193682 |
3.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1 |
ZN MG |
| 5IYC |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human core-PIC in the initial transcribing state |
27193682 |
3.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,EF A protein 1 |
ZN MG |
| 5IYD |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human core-PIC in the initial transcribing state (no IIS) |
27193682 |
3.90 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9,RPB10,RPB11,RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF |
ZN MG |
| 6DRD |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
RNA pol II(g) |
30190596 |
3.90Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,GRinL1A |
ZN |
| 6O9L |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Human holo-PIC in the closed state |
31110295 |
7.20 Å |
IC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TFIIA,TBP,TFIIE,TFIIF,TEFA protein 1,TFIIH,MAT1,CDK,Cyclin-H |
SF4[ IRON/SULFUR CLUSTER ] ZN MG |
| 2C35 |
XRD |
Eukaryote |
RNAP II |
Homo sapiens |
Subunits RPB4 and RPB7 of human RNA polymerase II |
16282592 |
2.70 Å |
RNAP |
RNAP II 16/19 kDa polypeptide |
|
| 1QKL |
SOLUTIONNMR |
Eukaryote |
RNAP II |
Homo sapiens |
Hrpabc14.4, essential subunit of human RNA polymerases I, II and III |
10542096 |
|
RNAP |
RNAP II 14.4 kDa polypeptide |
|
| 2DB9 |
SOLUTIONNMR |
Eukaryote |
RNAP II |
Homo sapiens |
Solution structure of the plus-3 domain of human KIAA0252 protein |
To be published. |
|
Subunit |
PAF1/RNA polymerase II complex |
|
| 7LBM |
EM |
Eukaryote |
RNAP II |
Homo sapiens |
Structure of the human Mediator-bound transcription pre-initiation complex |
33707221 |
4.80Å |
RNAP |
Isoform 2 of Mediator of RNA polymerase II transcription subunit 16,Mediator of RNA polymerase II transcription subunit 23,subunit 24,subunit 25,RNAP,Transcription initiation factor IIA subunit 1,subunit 2,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIE subunit 1,subunit beta,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,TFIIH basal transcription factor complex helicase XPB subunit,TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 4, p52,General transcription factor IIH subunit 2,General transcription factor IIH subunit 3,General transcription factor IIH subunit 5,CDK-activating kinase assembly factor MAT1,Cyclin-dependent kinase 7,Cyclin-H,Mediator of RNA polymerase II transcription subunit 6,subunit 8,subunit 11,subunit 17,subunit 18,subunit 20,subunit 22,subunit 27,subunit 28,subunit 29,subunit 30,subunit 14,subunit 4,subunit 7,subunit 9,subunit 10,subunit 19,subunit 21,subunit 31,subunit 15 |
SF4,ZN |
| 6A5R |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome |
30287617 |
8.70 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5L |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA |
30287617 |
5.60 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5O |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome |
30287617 |
9.90 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5P |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome |
30287617 |
7.00 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5T |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome |
30287617 |
6.70 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6A5U |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation |
30287617 |
7.60 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6inQ |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position) |
30287617 |
6.90 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B |
ZN MG |
| 6IR9 |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-1) of the nucleosome |
30733384 |
3.80 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4W |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-5) of the nucleosome |
30733384 |
7.90 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4X |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1a) |
30733384 |
4.30 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4Y |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex bound with ELF1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1b) |
30733384 |
4.30 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J4Z |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome |
30733384 |
4.10 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5 |
ZN MG |
| 6J51 |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome, weak ELF1 (+1 position) |
30733384 |
4.20 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5/4p |
ZN MG |
| 6J50 |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome (tilted conformation) |
30733384 |
4.70 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.3/H4/H2A/H2B,ELF1,Spt4/5/4p |
ZN MG |
| 7XN7 |
EM |
Eukaryote |
RNAP II |
Komagataella phaffii |
RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C |
35981082 |
3.10 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RNA polymerase II third largest subunit B44,RNA polymerase II subunit B32,RPABC1,RPABC23,RNA polymerase II subunit,RPABC3,RNA polymerase subunit ABC10-beta,RNA polymerase II subunit B12.5,RNA polymerase subunit ABC10-alpha,Transcription elongation factor 1 homolog,Transcription elongation factor SPT4,Chromatin elongation factor SPT5,Transcription elongation factor Spt6,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II,Component of the Paf1p complex,RNAPII-associated chromatin remodeling Paf1 complex subunit,Leo1,RNAP II-associated protein,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
ZN,MG |
| 1NT9 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete 12-subunit RNA polymerase II |
12746495 |
4.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 1PQV |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II-TFIIS complex |
12914699 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIS |
ZN MG |
| 1WCM |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete 12-subunit RNA polymerase II at 3.8 angstrom |
15591044 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 1Y14 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of yeast subcomplex of RPB4 and RPB7 |
15591044 |
2.30 Å |
RNAP |
RPB4,RPB7 |
|
| 1Y1V |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Refined RNA polymerase II-TFIIS complex |
15610738 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIS |
ZN MG |
| 1Y1W |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex |
15610738 |
4.00Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 1Y1Y |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II-TFIIS-DNA/RNA complex |
15610738 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 1Y77 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex with substrate analogue GMPCPP |
15610738 |
4.50Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 2B63 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II-RNA inhibitor complex |
16341226 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2B8K |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
12-subunit RNA polymerase II |
16765890 |
4.15Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 2JA5 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex A |
17290000 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2JA6 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex B |
17290000 |
4.00Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2JA7 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex C |
17290000 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2JA8 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
CPD lesion containing RNA polymerase II elongation complex D |
17290000 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2R7Z |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Cisplatin lesion containing RNA polymerase II elongation complex |
17994106 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
CPT[ Cisplatin ] ZN MG |
| 2R92 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Elongation complex of RNA polymerase II with artificial RDRP scaffold |
18004386 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2R93 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop |
18004386 |
4.00Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 2VUM |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Alpha-amanitin inhibited complete RNA polymerase II elongation complex |
18552824 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3FKI |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
12-subunit RNA polymerase II refined with Zn-SAD data |
19289466 |
3.88Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3H3V |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNAP II containing poly(A)-signal sequence in the active site |
19535338 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOU |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex I with a T-U mismatch |
19560423 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3HOV |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex II |
19560423 |
3.50Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOW |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3-uridine |
19560423 |
3.60Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOX |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex VI |
19560423 |
3.65Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOY |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex VI |
19560423 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3HOZ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3-guanine |
19560423 |
3.65Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3I4M |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
8-oxoguanine containing RNA polymerase II elongation complex D |
19758983 |
3.70Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3I4N |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
8-oxoguanine containing RNA polymerase II elongation complex E |
19758983 |
3.90Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3J0K |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Orientation of RNA polymerase II within the human VP16-mediator-pol II-TFIIF assembly |
21468301 |
36.0Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3J1N |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Cryo-EM map of a yeast minimal preinitiation complex interacting with the mediator head module |
22579255 |
16.0Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 3K1F |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of RNA polymerase II in complex with TFIIB |
19820686 |
4.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
ZN |
| 3PO2 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Arrested RNA polymerase II elongation complex |
21346759 |
3.30Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
EPE[ 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID?? PEG??DI(HYDROXYETHYL)ETHER] ZN MG ACT[ ACETATE ION ] |
| 3PO3 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Arrested RNA polymerase II reactivation intermediate |
21346759 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
EPE[ 4-(2-HYDROXYETHYL)-2-PIPERAZINE ETHANESULFONIC ACID?? PEG??DI(HYDROXYETHYL)ETHER ] ZN MG ACT[ ACETATE ION ] |
| 3QT1 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II variant containing a chimeric RPB9-C11 subunit |
21454497 |
4.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3B |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3C |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3D |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid |
22056778 |
3.40Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3E |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.40Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ IPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A3F |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ IPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A3G |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3I |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II binary complex with DNA |
22056778 |
3.80Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3J |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP |
22056778 |
3.70Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 4A3K |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4A3L |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.50Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A3M |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP |
22056778 |
3.90Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4A93 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex containing a CPD lesion |
22405652 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4BBR |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of RNA polymerase II-TFIIB complex |
23151482 |
3.40Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
ZN MG |
| 4BBS |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of an initially transcribing RNA polymerase II-TFIIB complex |
23151482 |
3.60Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB |
ZN MG |
| 4BXX |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Arrested RNA polymerase II-Bye1 complex |
24003114 |
3.28Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
ZN MG |
| 4BXZ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II-Bye1 complex |
24003114 |
4.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
ZN MG |
| 4BY1 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Elongating RNA polymerase II-Bye1 TLD complex soaked with AMPCPP |
24003114 |
3.60Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 4BY7 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Elongating RNA polymerase II-Bye1 TLD complex |
24003114 |
3.15Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription factor BYE1 |
EPE[ 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID ] ZN MG |
| 4V1N |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Architecture of the RNA polymerase II-mediator core transcription initiation complex |
25652824 |
7.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TBP,TFIIF subunit alpha,TFIIF subunit beta |
ZN MG |
| 4V1O |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Architecture of the RNA polymerase II-mediator core transcription initiation complex |
25652824 |
9.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TBP,TFIIF subunit alpha,TFIIF subunit beta,Mediator of RNA polymerase II transcription subunit 6/8/11/18/20/22 |
ZN MG |
| 5C3E |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
3.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5C44 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
3.95Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 5C4A |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
4.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5C4X |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5FMF |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
The P-lobe of RNA polymerase II pre-initiation complex |
26483468 |
6.00Å |
pIC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,DNA repair helicase RAD25 and SSL2,Transcription elongation factor S-II and DST1,RNA polymerase II pre-Initiation complex(TOA1),TFIIA subunit 2(TOA2), TFIIB(SUA7),TBP,TFIIE subunit alpha(TFA1),TFIIE subunit beta(TFA2),RNA polymerase II pre-Initiation complex (Tfg1),TFIIF subunit beta(TFG2),TFIIB subint 2(TFB2)/5(TFB5),DNA repair helicase RAD3 |
ZN MG |
| 5FYW |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Transcription initiation complex structures elucidate DNA opening (OC) |
27193681 |
4.35Å |
OC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,TFIIB,TBP,TFIIF subunit alpha,TFIIF subunit bata,TFIIA large subunit,TFIIA subunit 2,TFIIE subunit alpha,TFIIE subunit beta |
ZN MG |
| 5FZ5 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Transcription initiation complex structures elucidate DNA opening (CC) |
27193681 |
8.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit bata,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta |
ZN MG |
| 5IP7 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of RNA polymerase II-Tfg1 peptide complex |
27193681 |
3.52Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5IP9 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of RNA polymerase II-TFIIF complex |
27193681 |
3.90Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5OQJ |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of yeast transcription pre-initiation complex with TFIIH |
29088706 |
4.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,DNA repair helicase RAD3,RNA polymerase II transcription factor B subunit 1,RNA polymerase II transcription factor B subunit 2,RNA polymerase II transcription factor B subunit 3,RNA polymerase II transcription factor B subunit 4,RNA polymerase II transcription factor B subunit 5,Suppressor of stem-loop protein 1,DNA repair helicase RAD25 |
SF4[ IRON/SULFUR CLUSTER ] ZN MG |
| 5OQM |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of yeast transcription pre-initiation complex with TFIIH and core mediator |
29088706 |
5.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,subunit TFB2,subunit 3,subunit TFB4,subunit TFB5,subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Mediator of RNA polymerase II transcription subunit 6,subunit 8,subunit 11,subunit 17, subunit 18,subunit 20,subunit 22,subunit 4, subunit 7, subunit 9, subunit 10, subunit 14, subunit 19,subunit 21,subunit 31 |
SF4[ IRON/SULFUR CLUSTER ]ZN MG |
| 5OT2 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in the presence of 3D-Napht-A |
29087308 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
AHW[ 2-ethyl-7-methoxy-naphthalene ]ZN MG |
| 5SVA |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Mediator-RNA polymerase II pre-initiation complex |
27610567 |
15.3Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Mediator of RNA polymerase II transcription subunit 6,subunit 8,subunit 11,ubunit 17,subunit 18,subunit 20,subunit 22,subunit 4,subunit 7,subunit 9,subunit 21,subunit 31,DNA repair helicase RAD3,DNA repair helicase RAD25,RNA polymerase II transcription factor B subunit 2,RNA polymerase II transcription factor B subunit 5,Transcription initiation factor IIB,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,TBP,RPB1,Transcription initiation factor TFIID subunit 14 |
ZN MG |
| 5U5Q |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
12 subunit RNA polymerase II at room temperature collected using SFX |
28300169 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5VVR |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Ternary complex of RNA pol II, transcription scaffold and Rad26 |
29168508 |
5.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,DNA repair and recombination protein Rad26 |
ZN MG |
| 5VVS |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA pol II elongation complex |
29168508 |
6.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6GYK |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of a yeast closed complex (core CC1) |
30472190 |
5.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2 |
ZN MG |
| 6GYL |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of a yeast closed complex with distorted DNA (core CCdist) |
30472190 |
4.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Tfa1,Transcription initiation factor IIE subunit beta |
ZN MG |
| 6GYM |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of a yeast closed complex with distorted DNA (CCdist) |
30472190 |
6.70Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,General transcription and DNA repair factor IIH helicase subunit XPD,DNA repair helicase RAD3,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,RNA polymerase II transcription factor B subunit 4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,DNA repair helicase RAD25,Transcription initiation factor IIB,TBP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha |
SF4[ IRON/SULFUR CLUSTER ] ZN MG |
| 6I84 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of transcribing RNA polymerase II-nucleosome complex |
30575770 |
4.40Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Histone H3.2,Histone H2A type 1,Histone H4,Histone H2B 1.1 |
ZN MG |
| 1I3Q |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II crystal form I at 3.1 angstrom resolution |
11313498 |
3.10 Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MG |
| 1I50 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II crystal form II |
11313498 |
2.80 Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MN |
| 1I6H |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II enlongation complex |
11313499 |
3.30Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MG |
| 1K83 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of yeast RNA polymerase II complexed with the inhibitor alpha amanitin |
11805306 |
2.80 Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase II 27KD polypeptide,RNA polymerase II 23KD polypeptide,RNA polymerase II 14.5KD polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase II 8.3KD polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase II 7.7KD polypeptide |
ZN MG |
| 1NIK |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Wild type RNA polymerase II |
12746498 |
4.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 1R5U |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II TFIIB complex |
14963322 |
4.50Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide,TFIIB |
ZN MG |
| 1R9S |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II strand separated elongation complex, matched nucleotide |
15537538 |
4.25Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
UTP ZN MG |
| 1R9T |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II strand separated elongation complex, mismatched nucleotide |
15537538 |
3.50Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ATP ZN MG |
| 1SFO |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II strand separated elongation complex |
14963331 |
3.61Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ZN MG |
| 1TWA |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II complexed with ATP |
15537538 |
3.20Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ATP ZN MN |
| 1TWC |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II complexed with GTP |
15537538 |
3.00Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
GTP ZN MN |
| 1TWF |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II complexed with UTP at 2.3 angstrom resolution |
15537538 |
2.30Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
UTP ZN MN |
| 1TWG |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II complexed with CTP |
15537538 |
3.30Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
CTP ZN MN |
| 1TWH |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II complexed with dATP |
15537538 |
3.40Å |
RNAP |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27 kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II 14.2KD polypeptide,RNA polymerase I, II and III 8.3 kDa polypeptide,RNA polymerase II 13.6KD polypeptide,RNA polymerase I, II and III 7.7 kDa polypeptide |
ATP ZN MN |
| 2E2H |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex at 5 mm MG2+ with GTP |
17129781 |
3.95Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
GTP ZN MG |
| 2E2I |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 5 mm mg+2 with dGTP |
17129781 |
3.41Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
DGT[ 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE ] ZN MG |
| 2E2J |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 5 mm mg+2 with GMPCPP |
17129781 |
3.50Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 2L0I |
SOLUTIONNMR |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide |
20818393 |
|
RNAP |
Regulator of Ty1 transposition protein 103,DNA-directed RNA polymerase CTD |
|
| 2LO6 |
SOLUTIONNMR |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of Nrd1 CID bound to phosphorylated RNAP II CTD |
22892239 |
|
CTD |
Protein NRD1,RPB1 |
|
| 2NVQ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 150 mm mg+2 with dUTP |
17129781 |
2.90Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
DUT[ DEOXYURIDINE-5'-TRIPHOSPHATE ] ZN MG |
| 2NVT |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 150 mm mg+2 with GMPCPP |
17129781 |
3.36Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 2NVX |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 5 mm mg+2 with dUTP |
17129781 |
3.60Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
DUT[ DEOXYURIDINE-5'-TRIPHOSPHATE ] ZN MG |
| 2NVY |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II form II in 150 mm MN+2 |
17129781 |
3.40Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
ZN MN |
| 2NVZ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with UTP, updated 11/2006 |
17129781 |
4.30Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140KD polypeptide,RNA polymerase II 45KD polypeptide,RNA polymerase I, II and III 27kDa polypeptide,RNA polymerase I, II and III 23 kDa polypeptide,RNA polymerase I, II and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
UTP ZN MG |
| 2YU9 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex in 150 mm mg+2 with UTP |
17129781 |
3.40Å |
EC |
RNA polymerase II largest subunit,RNA polymerase II 140 kDa polypeptide,RNA polymerase II 45 kDa polypeptide,RNA polymerases I, II, and III 27 kDa polypeptide,RNA polymerases I, II, and III 23 kDa polypeptide,RNA polymerases I, II, and III 14.5 kDa polypeptide,RNA polymerase II subunit 9,RNA polymerases I/II/III subunit 10,RNA polymerase II 13.6 kDa polypeptide,RNA polymerases I, II, and III 7.7 kDa polypeptide |
UTP ZN MG |
| 3CQZ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin |
18538653 |
2.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,ALPHA-AMANITin |
ZN |
| 3GTG |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 12mer RNA |
19478184 |
3.78Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTJ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 13mer RNA |
19478184 |
3.42Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTK |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 18mer RNA |
19478184 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3GTL |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 13mer with g<>u mismatch |
19478184 |
3.38Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTM |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Co-complex of backtracked RNA polymerase II with TFIIS |
19478184 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription elongation factor S-II |
ZN MG |
| 3GTP |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 24mer RNA |
19478184 |
3.90Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3GTQ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex induced by damage |
19478184 |
3.80Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3K7A |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of an RNA polymerase II-TFIIB complex |
19965383 |
3.80Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,Transcription initiation factor IIB |
ZN |
| 3M3Y |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex C |
20448203 |
3.18Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
C7P[ cis-diammine(pyridine)chloroplatinum(II) ] ZN MG |
| 3RZD |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3RZO |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 4-nt RNA |
21798951 |
3.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 3S14 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 6-nt RNA |
21798951 |
2.85Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S15 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 7-nt RNA |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S16 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with an 8-nt RNA |
21798951 |
3.24Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3M4O |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex B |
20448203 |
3.57Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
C7P[ cis-diammine(pyridine)chloroplatinum(II) ] ZN MG |
| 3S17 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 9-nt RNA |
21798951 |
3.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S1M |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA (variant 1) |
21798951 |
3.13Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S1N |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA (variant 2) |
21798951 |
3.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S1Q |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt 3-deoxy RNA soaked with ATP |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ATP ZN MG |
| 3S1R |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt 3-deoxy RNA soaked with GTP |
21798951 |
3.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
GTP ZN MG |
| 3S2D |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 5-nt RNA containing a 5Br-U |
21798951 |
3.20Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 3S2H |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initiation complex with a 6-nt RNA containing a 2[prime]-iodo ATP |
21798951 |
3.30Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4V1M |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Architecture of the RNA polymerase II-mediator core transcription initiation complex |
25652824 |
6.60Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4X67 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of elongating yeast RNA polymerase II stalled at oxidative cyclopurine DNA lesions. |
25605892 |
4.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 4X6A |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of yeast RNA polymerase II encountering oxidative cyclopurine DNA lesions |
25605892 |
3.96Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN |
| 4Y52 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of 5-carboxycytosine recognition by RNA polymerase II during transcription elongation. |
26123024 |
3.50Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4Y7N |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
The structure insight into 5-carboxycytosine recognition by RNA polymerase II during transcription elongation. |
26123024 |
3.30Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
G2P[ PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER ] ZN MG |
| 5C4J |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble |
26186291 |
4.00Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5W4U |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Pol II elongation complex with an N6-methyladenine-containing template |
28933854 |
3.60Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 5W51 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Pol II elongation complex with an n6-methyladenine-containing template and a matched UMPNPP |
28933854 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
2KH[ 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine ] ZN MG |
| 6BLO |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I+1 position |
29487211 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6BLP |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I+1 position, soaking AMPCPP |
29487211 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[[DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 6BM2 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I-1 position |
29487211 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6BM4 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Pol II elongation complex with an abasic lesion at I-1 position,soaking UMPNPP |
29487211 |
2.95Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
2KH[ 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine ] ZN MG |
| 6BQF |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Pol II elongation complex with dt-apat I+1, I-1 position |
29487211 |
3.35Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6O6C |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex arrested at a CPD lesion |
31200019 |
3.10Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UPX |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1 |
32284409 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UPY |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2e |
32284409 |
3.40Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
APC[ DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER ]ZN MG |
| 6UPZ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3 |
32284409 |
3.10Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
PPV[ PYROPHOSPHATE ] ZN MG |
| 6UQ0 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 4 |
32284409 |
3.56Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UQ2 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with Dg in state 1 |
32284409 |
3.20Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UQ1 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6 |
32284409 |
3.60Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 6UQ3 |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5 |
32284409 |
3.47Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
PPV[ PYROPHOSPHATE ] ZN MG |
| 3GTO |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Backtracked RNA polymerase II complex with 15mer RNA |
19478184 |
4.00 Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 7KED |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with unnatural base dTPT3 |
34140682 |
3.60Å |
EM |
RNAP |
ZN,MG |
| 7KEE |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site |
34140682 |
3.45Å |
EM |
RNAP |
WCG [insert into `user` values (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol],ZN,MG |
| 7KEF |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state |
34140682 |
3.89Å |
EM |
RNAP |
WCG [insert into `user` values (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol],ZN,MG |
| 7RIQ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex scaffold 1 without polyamide |
35022237 |
3.00Å |
EM |
RNAP |
ZN,MG |
| 7RIM |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 |
35022237 |
2.90Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIQ |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 soaked with CTP
|
35022237 |
3.30Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIW |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex scaffold 2, without polyamide
|
35022237 |
3.20Å |
EM |
RNAP |
ZN,MG |
| 7RIX |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2
|
35022237 |
3.40Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIP |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 soaked with CTP
|
35022237 |
3.30Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7RIY |
XRD |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2 soaked with UTP
|
35022237 |
3.70Å |
EM |
RNAP |
5N0[3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[insert into `user` values (1-methyl-4-{[1-methyl-4-({1-methyl-4-[insert into `user` values (1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-ca |
| 7ML4 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initially transcribing complex (ITC) |
35051353 |
3.10Å |
IC |
RNAP,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIB,BJ4_G0050160.mRNA.1.CDS.1,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH,Tfb1,General transcription and DNA repair factor IIH helicase subunit XPB,General transcription and DNA repair factor IIH subunit TFB5,RNA polymerase II transcription factor B subunit 2,Transcription initiation factor IIE subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,TATA-box-binding protein,Transcription initiation factor IIE subunit alpha |
SF4,MG,ZN |
| 7MEI |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Composite structure of EC+EC |
35051353 |
3.54Å |
EC |
RNAP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta |
MG,ZN |
| 7MK9 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complex structure of trailing EC of EC+EC (trailing EC-focused) |
35051353 |
3.54Å |
EC |
RNAP,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta |
MG,ZN |
| 7MKA |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complex structure of trailing EC of EC+EC (trailing EC-focused) |
35051353 |
3.54Å |
EC |
RNAP |
MG,ZN |
| 7ML1 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II pre-initiation complex (PIC2) |
35051353 |
4.00Å |
PIC |
RNAP,Tfb1,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit SSL1,RNA polymerase II transcription factor B subunit 2,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH helicase subunit XPB,BJ4_G0050160.mRNA.1.CDS.1,TATA-box-binding protein,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta |
SF4,MG,ZN |
| 7ML2 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II pre-initiation complex (PIC3) |
35051353 |
3.40Å |
PIC |
RNAP,Tfb1,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,BJ4_G0004860.mRNA.1.CDS.1,Tfb1,Tfb4,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH,RNA polymerase II transcription factor B subunit 2,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH helicase subunit XPB,BJ4_G0050160.mRNA.1.CDS.1 |
SF4,MG,ZN |
| 7ML4 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II initially transcribing complex (ITC) |
35051353 |
3.10Å |
PIC |
RNAP,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIB,BJ4_G0050160.mRNA.1.CDS.1,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH,Tfb1,General transcription and DNA repair factor IIH helicase subunit XPB,General transcription and DNA repair factor IIH subunit TFB5,RNA polymerase II transcription factor B subunit 2,Transcription initiation factor IIE subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,TATA-box-binding protein,Transcription initiation factor IIE subunit alpha |
SF4,MG,ZN |
| 7O4I |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble |
34133942 |
3.20Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O4J |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex (consensus) |
34133942 |
2.90Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O4K |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast TFIIH in the contracted state within the pre-initiation complex |
34133942 |
3.60Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O4L |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast TFIIH in the expanded state within the pre-initiation complex |
34133942 |
3.40Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O72 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA |
34133942 |
3.40Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O73 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA |
34133942 |
3.40Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB2,subunit TFB1,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7O75 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA |
34133942 |
3.20Å |
PIC |
RNAP,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB2,subunit TFB1,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA large subunit,subunit 2,Transcription initiation factor IIE subunit alpha,subunit beta |
ADP,SF4,BEF,MG,ZN |
| 7ML0 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
RNA polymerase II pre-initiation complex (PIC1) |
35051353 |
3.00Å |
PIC |
RNAP,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,TATA-box-binding protein,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit SSL1,RNA polymerase II transcription factor B subunit 2,General transcription and DNA repair factor IIH subunit TFB5,BJ4_G0050160.mRNA.1.CDS.1,General transcription and DNA repair factor IIH helicase subunit XPB |
SF4,MG,ZN |
| 7MKA |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Structure of EC+EC (leading EC-focused) |
|
3.54 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC5,RPABC4 |
ZN,MG |
| 7MK9 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Complex structure of trailing EC of EC+EC (trailing EC-focused) |
|
3.54 Å |
EC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta |
ZN,MG |
| 7ZS9 |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) |
36411341 |
3.10 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 7ZSA |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B) |
36411341 |
4.00 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 7ZSB |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae |
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C |
36411341 |
6.60 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,TATA-box-binding protein,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription initiation factor IIA large subunit,Transcription initiation factor IIA subunit 2,Transcription initiation factor IIE subunit alpha,Transcription initiation factor IIE subunit beta,General transcription and DNA repair factor IIH helicase subunit XPD,General transcription and DNA repair factor IIH subunit TFB1,General transcription and DNA repair factor IIH subunit TFB2,RNA polymerase II transcription factor B subunit 3,General transcription and DNA repair factor IIH subunit TFB4,General transcription and DNA repair factor IIH subunit TFB5,General transcription and DNA repair factor IIH subunit SSL1,General transcription and DNA repair factor IIH helicase subunit XPB,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
SF4[IRON/SULFUR CLUSTER],ZN,MG |
| 7UIO |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae S288C |
Mediator-PIC Early (Composite Model) |
36731470 |
3.30 Å |
PIC |
Mediator of RNA polymerase II transcription subunit 15,1,2,3,4,6,7,8,9,10,11,14,5,16,17,18,19,20,21,22,31,Regulatory protein GAL4,RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription elongation factor S-II |
ASP[ASPARTIC ACID],THR[THREONINE],ALA[ALANINE],ZN |
| 7UIF |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae S288C |
Mediator-PIC Early (Core B) |
36731470 |
4.60 Å |
PIC |
RPB1,RPB2,RPB3,RPB4,RPB7,RPB9,RPB11,RPABC1,RPABC2,RPABC3,RPABC4,RPABC5,Transcription initiation factor IIB,Transcription initiation factor IIF subunit alpha,Transcription initiation factor IIF subunit beta,Transcription elongation factor S-II,Mediator of RNA polymerase II transcription subunit 1,4,6,7,8,9,10,11,14,17,18,19,20,21,22,31 |
|
| 7NKY |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae, Xenopus laevis |
RNA Polymerase II-Spt4/5-nucleosome-FACT structure |
33846633 |
3.20Å |
RNAP |
RNAP,Chromatin elongation factor SPT4,Transcription elongation factor SPT5,FACT complex subunit POB3,FACT complex subunit SPT16,Histone H3.2,Histone H4,Histone H2A type 1,Histone H2B 1.1 |
MG,ZN |
| 7NKX |
EM |
Eukaryote |
RNAP II |
Saccharomyces cerevisiae, Xenopus laevis |
RNA polymerase II-Spt4/5-nucleosome-Chd1 structure |
33846633 |
2.90Å |
RNAP |
RNAP,Histone H3.2,Histone H4,Histone H2A type 1,Histone H2B 1.1,Chromo domain-containing protein 1,Chromatin elongation factor SPT4,Chromatin elongation factor SPT5 |
ADP,BEF,MG,ZN |
| 3H0G |
XRD |
Eukaryote |
RNAP II |
Schizosaccharomyces pombe |
RNA polymerase II from schizosaccharomyces pombe |
19458260 |
3.65 Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
ZN MG |
| 4PZ6 |
XRD |
Eukaryote |
RNAP II |
Schizosaccharomyces pombe |
PCE1 guanylyltransferase bound to Ser2/Ser5 phosphorylated RNA pol II CTD |
24939935 |
2.41Å |
RNAP |
mRNA-capping enzyme subunit alpha, RPB1 |
GMP |
| 5U0S |
EM |
Eukaryote |
RNAP II |
Schizosaccharomyces pombe |
Cryo-EM structure of the mediator-RNAPII complex |
28241144 |
7.80Å |
RNAP |
Mediator complex subunit 6,Mediator complex subunit 8,Mediator complex subunit 17,Mediator complex subunit 18,Mediator complex subunit 20,Mediator complex subunit 11,Mediator complex subunit 22,Mediator complex subunit 14,Mediator complex subunit 4,Mediator complex subunit 7,Mediator complex subunit 21,Mediator complex subunit 31,Mediator complex subunit 27,Mediator complex subunit 9,Mediator complex subunit 19,Mediator complex subunit 10,RPB1, RPB2,RPB3,RPB4, RPB5,RPB6,RPB7,RPB8,RPB9,RPB10, RPB11,RPB12 |
|
| 6EXV |
EM |
Eukaryote |
RNAP II |
Sus scrofa |
Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin |
29550768 |
3.60 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12 |
|
| 6GMH |
EM |
Eukaryote |
RNAP II |
Sus scrofa |
Structure of activated transcription complex pol II-DSIF-paf-SPT6 |
30135578 |
3.10Å |
RNAP |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,SPT6,CTR9,LEO1,PAF1,WD repeat-containing protein 61,CDC73,Spt4,Spt5 |
ZN MG |
| 6GML |
EM |
Eukaryote |
RNAP II |
Sus scrofa |
Structure of paused transcription complex pol II-DSIF-NELF |
30135580 |
3.20Å |
EC |
DNA-directed RNA polymerase subunit,beta,C,E,F,RPABC3,RPB9,Negative elongation factor A,Negative elongation factor B,Negative elongation factor C/D,Negative elongation factor E,Spt4,Spt5,D,G |
ZN MG |
| 6TED |
EM |
Eukaryote |
RNAP II |
Sus scrofa |
Structure of complete, activated transcription complex pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 |
32541898 |
3.10 Å |
EC |
RPB1,RPB2,RPB3,RPB4,RPB5,RPB6,RPB7,RPB8,RPB9, RPB10,RPB11, RPB12,CTR9 homolog, RTF1 homolog,LEO1,RAF1,WD repeat-containing protein 61,Spt4/5/6 |
ZN MG |
| 7OZP |
EM |
Eukaryote |
RNAP II |
Sus scrofa domesticus |
RNA Polymerase II dimer (Class 3)
|
34530439 |
3.80Å |
RNAP |
RNAP |
ZN |
| 7OZN |
EM |
Eukaryote |
RNAP II |
Sus scrofa domesticus |
RNA Polymerase II dimer (Class 1)
|
34530439 |
3.50Å |
RNAP |
RNAP |
ZN |
| 7OZO |
EM |
Eukaryote |
RNAP II |
Sus scrofa domesticus |
RNA Polymerase II dimer (Class 2)
|
34530439 |
3.80Å |
RNAP |
RNAP |
ZN |
| 7B7U |
EM |
Eukaryote |
RNAP II |
Sus scrofa domesticus, Homo sapiens |
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 |
34021257 |
2.80Å |
RNAP |
RNAP |
ZN |
| 7NVU |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
RNA polymerase II core pre-initiation complex with open promoter DNA |
33902107 |
2.50Å |
PIC |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,subunit 1,General transcription factor IIE subunit 1,subunit beta |
MG,ZN |
| 7NVU |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
RNA polymerase II core pre-initiation complex with open promoter DNA |
33902107 |
2.50Å |
PIC |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,subunit 1,General transcription factor IIE subunit 1,subunit beta |
MG,ZN |
| 7NVZ |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
RNA polymerase II pre-initiation complex with closed promoter DNA in distal position |
33902107 |
7.20Å |
PIC |
TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,subunit 4,subunit 3,subunit 5,subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,CDK-activating kinase assembly factor MAT1,RNAP,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,subunit 2,Transcription initiation factor IIA subunit 1,General transcription factor IIE subunit 1,subunit beta |
SF4,MG,ZN |
| 7F4G |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Structure of RPAP2-bound RNA polymerase II |
35476980 |
2.78Å |
RNAP |
RNAP |
ZN |
| 7NVY |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position |
33902107 |
7.30Å |
PIC |
TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,subunit 4,subunit 3,subunit 5,subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,CDK-activating kinase assembly factor MAT1,RNAP,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,subunit 2,Transcription initiation factor IIA subunit 1,General transcription factor IIE subunit 1,subunit beta,CDK-activating kinase assembly factor MAT1 |
SF4,MG,ZN |
| 7NW0 |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
RNA polymerase II pre-initiation complex with open promoter DNA |
33902107 |
6.60Å |
PIC |
TFIIH basal transcription factor complex helicase XPD subunit,General transcription factor IIH subunit 1,subunit 4,subunit 3,subunit 5,subunit 2,General transcription and DNA repair factor IIH helicase subunit XPB,CDK-activating kinase assembly factor MAT1,RNAP,RNA_pol_L_2 domain-containing protein,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,subunit 2,Transcription initiation factor IIA subunit 1,General transcription factor IIE subunit 1,subunit beta,CDK-activating kinase assembly factor MAT1 |
ADP,BEF,SF4,MG,ZN |
| 7B0Y |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Structure of a transcribing RNA polymerase II-U1 snRNP complex |
33446560 |
3.60Å |
RNAP |
RNAP,U1 small nuclear ribonucleoprotein 70 kDa,U1 small nuclear ribonucleoprotein A,Small nuclear ribonucleoprotein Sm D2,Small nuclear ribonucleoprotein F,Small nuclear ribonucleoprotein E,Small nuclear ribonucleoprotein G,Small nuclear ribonucleoprotein Sm D3,Small nuclear ribonucleoprotein-associated protein,Small nuclear ribonucleoprotein Sm D1 |
MG,ZN |
| 7OO3 |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Pol II-CSB-CSA-DDB1-UVSSA (Structure1) |
34526721 |
2.80Å |
RNAP |
RNAP,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,CSB element,UV-stimulated scaffold protein A,DNA damage-binding protein 1 |
ZN,MG |
| 7OOB |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) |
34526721 |
2.70Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,DNA excision repair protein ERCC-6,DNA damage-binding protein 1,DNA excision repair protein ERCC-8 |
ADP,BEF,ZN,MG |
| 7OOP |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) |
34526721 |
2.90Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription elongation factor SPT6,LEO1 helix,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WD repeat-containing protein 61,Parafibromin,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,UV-stimulated scaffold protein A,DNA damage-binding protein 1 |
ZN,MG |
| 7OPC |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) |
34526721 |
3.00Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription elongation factor SPT6,LEO1 helix,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WD repeat-containing protein 61,Parafibromin,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,UV-stimulated scaffold protein A,DNA damage-binding protein 1,Cullin-4A,E3 ubiquitin-protein ligase RBX1 |
ZN,MG |
| 7OPD |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) |
34526721 |
3.00Å |
RNAP |
RNAP,RPOL4c domain-containing protein,RNA_pol_L_2 domain-containing protein,Transcription elongation factor SPT6,LEO1 helix,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WD repeat-containing protein 61,Parafibromin,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-6,UV-stimulated scaffold protein A,DNA damage-binding protein 1,Cullin-4A,E3 ubiquitin-protein ligase RBX1 |
ZN,MG |
| 7ZWD |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) |
36424526 |
3.00 Å |
PIC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RNA polymerase II subunit D,E,F,J,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,snRNA-activating protein complex subunit 1,snRNA-activating protein complex subunit 3,snRNA-activating protein complex subunit 4,snRNA-activating protein complex subunit 5 |
ZN,MG |
| 7ZX7 |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) |
36424526 |
3.40 Å |
PIC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RNA polymerase II subunit D,E,F,J,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,snRNA-activating protein complex subunit 1,snRNA-activating protein complex subunit 3,snRNA-activating protein complex subunit 4,snRNA-activating protein complex subunit 5 |
ZN,MG |
| 7ZX8 |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens |
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) |
36424526 |
3.00 Å |
PIC |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB9,RPABC3,RPABC5,RNA polymerase II subunit D,E,F,J,K,Transcription initiation factor IIB,TATA-box-binding protein,General transcription factor IIF subunit 1,General transcription factor IIF subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 2,snRNA-activating protein complex subunit 1,snRNA-activating protein complex subunit 3,snRNA-activating protein complex subunit 4,snRNA-activating protein complex subunit 5 |
ZN,MG |
| 7OL0 |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens, HIV whole-genome vector AA1305#18 |
Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) |
34265249 |
3.00Å |
EC |
RNAP,Transcription elongation factor SPT5 |
ZN,MG |
| 7OKX |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens, HIV whole-genome vector AA1305#18 |
Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure) |
34265249 |
3.30Å |
EC |
RNAP,RNA polymerase II elongation factor ELL2,ELL-associated factor 1,Transcription elongation factor SPT5 |
ZN,MG |
| 7OKY |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens, HIV whole-genome vector AA1305#18 |
Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) |
34265249 |
4.14Å |
EC |
RNAP,RNA polymerase II elongation factor ELL2,ELL-associated factor 1,Transcription elongation factor SPT5,Transcription elongation factor SPT5 |
ZN,MG |
| 7UND |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens, Xenopus laevis |
Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) |
35709268 |
3.00 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB8,RPB9,RPB10,RPB11,RPOL4c domain-containing protein,DNA-directed RNA polymerase II subunit E,RPABC2,RNA polymerase II subunit K,Transcription elongation factor SPT6,Transcription elongation factor A protein 1,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein RTF1 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WDR61,Parafibromin,Transcription elongation factor SPT4,Transcription elongation factor SPT5,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
ZN,MG |
| 7UNC |
EM |
Eukaryote |
RNAP II |
Sus scrofa, Homo sapiens,Xenopus laevis |
Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome |
35709268 |
3.00 Å |
RNAP |
DNA-directed RNA polymerase subunit,DNA-directed RNA polymerase subunit beta,RPB3,RPB7,RPB8,RPB9,RPB10,RPB11,RPOL4c domain-containing protein,DNA-directed RNA polymerase II subunit E,RPABC2,RNA polymerase II subunit K,Transcription elongation factor SPT6,Transcription elongation factor A protein 1,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein RTF1 homolog,RNA polymerase-associated protein LEO1,RNA polymerase II-associated factor 1 homolog,WDR61,Parafibromin,Transcription elongation factor SPT5,Histone H3.2,Histone H4,Histone H2A,Histone H2B 1.1 |
ZN,MG |